A model learns symptom-drug relations for PD patients.
arXiv research
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Dynamic treatment recommendation systems based on large-scale electronic health records (EHRs) become a key to successfully improve practical clinical outcomes. Prior relevant studies recommend treatments either use supervised learning (e.g. matching the indicator signal which denotes doctor prescriptions), or reinforc…
The paper integrates AI and expert knowledge to optimize radiotherapy decisions.
Laboratory testing and medication prescription are two of the most important routines in daily clinical practice. Developing an artificial intelligence system that can automatically make lab test imputations and medication recommendations can save costs on potentially redundant lab tests and inform physicians of a more…
This paper presents an automated approach for interpretable feature recommendation for solving signal data analytics problems. The method has been tested by performing experiments on datasets in the domain of prognostics where interpretation of features is considered very important. The proposed approach is based on Wi…
New recommendations improve Gaussian process accuracy and stability.
We augment linear Support Vector Machine (SVM) classifiers by adding three important features: (i) we introduce a regularization constraint to induce a sparse classifier; (ii) we devise a method that partitions the positive class into clusters and selects a sparse SVM classifier for each cluster; and (iii) we develop a…
Dr.S recommends cancer drugs based on genomic data.
PNNs improve treatment outcomes in TAVR and liver trauma.
The Prescriptive Canvas improves business outcomes by directly prescribing actions based on predictions.
A new neural network model for optimal treatment assignment.
Paper integrates predictive and prescriptive tasks using bilevel optimization.
Opioid overdose rates have reached an epidemic level and state-level policy innovations have followed suit in an effort to prevent overdose deaths. State-level drug law is a set of policies that may reinforce or undermine each other, and analysts have a limited set of tools for handling the policy collinearity using st…
We address the problem of prescribing an optimal decision in a framework where the cost function depends on uncertain problem parameters that need to be learned from data. Earlier work proposed prescriptive formulations based on supervised machine learning methods. These prescriptive methods can factor in contextual in…
The opioid epidemic in the United States claims over 40,000 lives per year, and it is estimated that well over two million Americans have an opioid use disorder. Over-prescription and misuse of prescription opioids play an important role in the epidemic. Individuals who are prescribed opioids, and who are diagnosed wit…
Deep learning predicts drug prescriptions across global health records.
ODTLearn learns optimal decision trees for predictive and prescriptive tasks.
Accounting frameworks follow stipulations of existing Accounting Theories. This exploratory research sets out to trace the evolution of accounting theories of Charge and Discharge Syndrome and the Corollary of Double Entry. Furthermore, it dives into the theories of Income Determination, garnishing it with areas of div…
Local classification of surfaces and hypersurfaces with radial mean curvature.
Paper uses RL to optimize daily step distribution for better health biomarkers.
Paper solves curvature prescription problem on surfaces with boundary.
This paper addresses a novel data science problem, prescriptive price optimization, which derives the optimal price strategy to maximize future profit/revenue on the basis of massive predictive formulas produced by machine learning. The prescriptive price optimization first builds sales forecast formulas of multiple pr…
Current clinical practice guidelines for managing Coronary Artery Disease (CAD) account for general cardiovascular risk factors. However, they do not present a framework that considers personalized patient-specific characteristics. Using the electronic health records of 21,460 patients, we created data-driven models fo…
P.Lecomte has proposed to take into account the covariant derivatives used to build ordering prescriptions for the naturality of transformation properties and has conjectured that there exists an natural ordering prescription for differential operators of any orders between density bundles which in addition is invarian…
The study compares Euclidean and cosine distances in medical drug prescription prediction.
Machine-assisted treatment recommendations hold a promise to reduce physician time and decision errors. We formulate the task as a sequence-to-sequence prediction model that takes the entire time-ordered medical history as input, and predicts a sequence of future clinical procedures and medications. It is built on the …
New approach for estimating individual treatment effects in low compliance settings.
Prescribing, by conformal transformation, the kth-elementary symmetric polynomial of the Schouten tensor to be constant is a generalisation of the Yamabe problem. On compact Riemannian n-manifolds we show that, for k between and including 3 and n, this prescription equation is an Euler-Lagrange equation of some act…
Study proves curvature prescription on spheres for k ≥ n/2.
End-to-end pipeline for data-driven decision making in mixed-integer optimization.
In this paper we give a new proof of a theorem by Alexandrov on the Gauss curvature prescription of Euclidean convex sets. This proof is based on the duality theory of convex sets and on optimal mass transport. A noteworthy property of this proof is that it does not rely neither on the theory of convex polyhedra nor on…
Method learns optimal treatment policies from observational data.
Two problems concerning asymptotically hyperbolic manifolds with an inner boundary are studied. First, we study scalar curvature presciption with either Dirichlet or mean curvature prescription interior boundary condition. Then we apply those results to the Lichnerowicz equation with (future or past) apparent horizon i…
PNNs improve personalized healthcare policies using mixed integer programming.
In this paper, we study conformal invariants that arise from nodal sets and negative eigenvalues of conformally covariant operators; more specifically, the GJMS operators, which include the Yamabe and Paneitz operators. We give several applications to curvature prescription problems. We establish a version in conformal…
For any compact manifold of dimension n>=5, we prescribe the volume and any finite part of the spectrum of the Hodge Laplacian acting on diffential forms of degree 1<p<n-1 (exept for p=n/2 if n is even), within a given conformal class. When n<5 and when p=0,1,n-1,n, and p=n/2 if n is even, this simultaneous prescriptio…
We prove that, for a generic set of smooth prescription functions on a closed ambient manifold, there always exists a nontrivial, smooth, closed hypersurface of prescribed mean curvature . The solution is either an embedded minimal hypersurface with integer multiplicity, or a non-minimal almost embedded hypersur…
A new framework for optimizing interventions with limited data.
We prove existence of compact spacelike hypersurfaces with prescribed k - curvature in de Sitter space, where the prescription function depends on both space and the tilt function.
Solves curvature prescription on rotational surfaces.
We extend our studies of a quantum field model defined on a lattice having the dilation group as a local gauge symmetry. The model is relevant in the cross-disciplinary area of econophysics. A corresponding proposal by Ilinski aimed at gauge modeling in non-equilibrium pricing is realized as a numerical simulation of t…
We can overcome uncertainty with uncertainty. Using randomness in our choices and in what we control, and hence in the decision making process, could potentially offset the uncertainty inherent in the environment and yield better outcomes. The example we develop in greater detail is the news-vendor inventory management…
Let be an open Riemann surface and be an integer. We prove that on any closed discrete subset of one can prescribe the values of a conformal minimal immersion . Our result also ensures jet-interpolation of given finite order, and hence, in particular, one may in addition prescribe the…
In this paper it is hown that given any smooth, positive function f on a closed, smooth manifold of dimension greater than four and with positive Paneitz invariant, there exists a metric on M such that = f.
The paper solves curvature prescription on a disk with negative Gaussian curvature.
Study uses holography to analyze entanglement entropy in deformed CFTs.
New approach makes deep reinforcement learning robust without assuming adversary knowledge.
In this note we establish the large time non-negativity of the heat kernel for a class of elliptic differential operators on closed, Riemannian manifolds, and apply this result to a problem from conformal differential geometry.