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arXiv research

A locally-built, LLM-digested index of recent arXiv papers in quant finance, geometry/topology, and statistical ML — keyword search served straight from SQLite on this machine.

168,742 papers · 148 categories

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2585177751,033 · Jun 202019922001200920172026
48 results for Precision Disease Networks

rags2ridges simplifies graphical modeling of high-dimensional data.

problem Graphical modeling of high-dimensional precision matrices.
method Modular framework for extraction, visualization, and analysis of Gaussian graphical models.
result Provides a one-stop-shop for graphical modeling of high-dimensional precision matrices.

AdaptiveNet tackles disease progression prediction in rheumatoid arthritis using deep neural networks.

problem Predicting disease progression in rheumatoid arthritis using clinical data.
method AdaptiveNet, a novel recurrent neural network architecture, that handles multiple lists of different events and missing data.
result AdaptiveNet outperforms classical baselines in disease progression prediction.

Novel approach combines local and global brain changes for AD prediction.

problem Detecting Alzheimer's disease through local and global brain changes.
method Patch-based 3D-CNNs combined with global topological features for multi-scale brain tissue connectivity.
result Average precision score of 0.95 for classifying cognitively normal subjects and AD patients (prevalence ~55%).

New method uses probabilistic independence to discover disease signatures from medical records.

problem Insufficiently precise diagnosis of clinical disease leading to treatment failures.
method Unsupervised machine learning using probabilistic independence to disentangle disease patterns.
result Inferred 2000 clinical disease signatures from medical records, improving cancer prediction.

Chronic Pulmonary Aspergillosis (CPA) is a complex lung disease caused by infection with Aspergillus. Computed tomography (CT) images are frequently requested in patients with suspected and established disease, but the radiological signs on CT are difficult to quantify making accurate follow-up challenging. We propose …

2019-02-06abs ↗pdf ↗

Today, despite decades of developments in medicine and the growing interest in precision healthcare, vast majority of diagnoses happen once patients begin to show noticeable signs of illness. Early indication and detection of diseases, however, can provide patients and carers with the chance of early intervention, bett…

2019-07-22abs ↗pdf ↗

Hierarchical CNNs improve diagnosis of GI diseases from histopathological images.

problem Diagnosing GI diseases from histopathological images is challenging due to heterogeneity and shared features.
method Embedded a class hierarchy into a VGGNet to address the hierarchical structure of GI diseases.
result The hierarchical model achieved better results than a flat model for multi-category diagnosis of GI disorders.

Deep Belief Network predicts lncRNA-disease associations with high accuracy.

problem Accurately identifying lncRNA-disease associations to understand lncRNA functionality and disease mechanism.
method Proposes a DBN-based model using heterogeneous networks and DBN for feature learning.
result Obtained AUC of 0.96 and AUPR of 0.967 on standard dataset.

A method to explain disease transformation using biomarker covariance matrices.

problem Understanding disease transformation from a healthy baseline.
method Modeling healthy and disease states of biomarker covariance matrices to characterize perturbations.
result Disease perturbs the biomarker covariance structure, allowing for mechanistic explanations and individual patient prognosis.

Study improves machine learning models for GI tract disease detection using comprehensive evaluations and cross-dataset testing.

problem Incomplete or incorrect evaluation of machine learning models for GI tract diseases.
method Comprehensive evaluations of five machine learning models using Global Features and Deep Neural Networks, introducing performance hexagons and cross-dataset testing.
result Demonstrates the need for more sophisticated performance metrics and evaluation methods to build generalizable models.

Omics-GAN uses GANs to generate synthetic multi-omics data for improved disease prediction.

problem Limited sample sizes, noise, and heterogeneity in multi-omics data reduce predictive power.
method Omics-GAN is a GAN-based framework that generates high-quality synthetic multi-omics profiles.
result Synthetic datasets consistently improved prediction accuracy compared to original omics profiles.

HMRNN combines HMMs and neural networks for Alzheimer's disease forecasting.

problem Improving disease progression modeling with hidden states not fully known.
method Developed HMRNN combining HMMs and recurrent neural networks.
result HMRNN improves disease forecasting and offers novel clinical interpretation.

CNNs accurately measure airways and vessels on CT images, improving lung disease diagnosis.

problem Accurately characterizing small pulmonary structures from CT images for disease diagnosis.
method Generative model combined with Convolutional Neural Regressor (CNR) for cross-sectional measurements.
result CNNs provide accurate measurements with physiological correlates.

Graph network predicts circRNA-disease associations using multi-source similarity features.

problem Identifying circRNA-disease associations is challenging and time-consuming.
method Proposes a graph convolution network framework using multi-source similarity information.
result Framework predicts circRNA-disease associations with promising results and outperforms existing methods.

Framework integrates mental disorder measurements for personalized treatment.

problem Optimizing treatment for mental disorders with latent mental states and heterogeneity.
method Measurement theory and multi-layer neural network for complex treatment effects.
result Learned treatment policies outperform alternatives on heterogeneous treatment effects.

ENN method uses expectile regression for genetic data analysis of complex diseases.

problem Discover additional genetic variants contributing to complex diseases.
method Developed an expectile neural network (ENN) method integrating expectile regression and neural networks.
result ENN method outperforms existing expectile regression in discovering genetic variants predisposing to sub-populations.

MOTGNN integrates multi-omics data for disease classification with improved accuracy and interpretability.

problem Challenges in integrating multi-omics data due to high dimensionality, heterogeneity, and lack of reliable interaction networks.
method MOTGNN uses XGBoost for graph construction, modality-specific GNNs for representation learning, and a deep feedforward network for cross-omics integration.
result MOTGNN outperforms state-of-the-art baselines by 5-10% in accuracy, ROC-AUC, and F1-score across three real-world disease datasets.

DDP models dynamic comorbidity networks from event data.

problem Understanding complex temporal patterns of co-occurring diseases.
method Developed deep diffusion processes (DDP) to model dynamic comorbidity networks.
result DDP enables accurate risk prediction and interpretable disease trajectories.

RL algorithms with medical integration improve personalized treatment recommendations.

problem Developing effective personalized treatment strategies for chronic diseases.
method Integrating medical knowledge into RL algorithms for DTR.
result Enhanced treatment recommendations with increased confidence.

Bayesian approach models neurodegenerative diseases without clinical labels.

problem Personalized, predictive modeling of neurodegenerative diseases.
method Probabilistic programmed deep kernel learning combining Gaussian processes and neural networks.
result Surpasses deep learning in accuracy and timeliness of predicting neurodegeneration.

Novel method identifies proteomic risk markers for Alzheimer disease.

problem Lack of comprehensive proteomic risk markers for Alzheimer disease diagnosis.
method Deep belief network-based feature selection method using proteomic and clinical data.
result Identified an optimal subset of proteins achieving 90% accuracy in Alzheimer disease diagnosis.

One primary task of population health analysis is the identification of risk factors that, for some subpopulation, have a significant association with some health condition. Examples include finding lifestyle factors associated with chronic diseases and finding genetic mutations associated with diseases in precision he…

2018-11-27abs ↗pdf ↗

Generative model designs drug combinations for improved efficacy and reduced side effects.

problem Designing effective drug combinations to overcome resistance and reduce side effects.
method Developed a deep generative model using HVGAE and a novel reward system.
result Network-principled drug combinations show reduced toxicity and potential for new strategies.

VEGN uses graph neural networks to predict disease-causing mutations from genetic variants.

problem Identifying disease-causing mutations from millions of genetic variants.
method VEGN employs a graph neural network on a heterogeneous graph of genes and variants, learning gene-gene interactions.
result VEGN outperforms existing state-of-the-art models in variant effect prediction.

Paper classifies Parkinson's disease from speech in three languages using CNNs and transfer learning.

problem Classifying Parkinson's disease from speech in multiple languages.
method Convolutional Neural Networks (CNNs) with transfer learning among Spanish, German, and Czech.
result Transfer learning improves model accuracy by up to 8% and balances specificity-sensitivity.

AI-assisted heart disease diagnosis reduces misdiagnosis and saves lives.

problem Misdiagnosis of heart disease leads to unnecessary deaths.
method Developed an AI application using ML and DNN algorithms on a dataset from the Cleveland Clinic Foundation.
result DNN model achieved a 92% accuracy rate, reducing misdiagnosis.