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arXiv research

A locally-built, LLM-digested index of recent arXiv papers in quant finance, geometry/topology, and statistical ML — keyword search served straight from SQLite on this machine.

168,786 papers · 148 categories

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1234 · May 202619922001200920172026
48 results for Pediatric Oncology

Study identifies subphenotypes of pediatric sepsis to improve ML predictive performance.

problem Enhance machine learning predictive performance in pediatric sepsis.
method Latent profile analysis of clinical data to identify subphenotypes, followed by ML experiments.
result Improved predictive performance of ML models targeting specific subphenotypes of pediatric sepsis.

Develops a fast non-invasive tool for diagnosing pediatric sleep apnea.

problem Diagnosing pediatric obstructive sleep apnea using an overnight sleep study is often impractical.
method Combines persistent homology, geometric shape analysis, and convolutional neural networks to classify facial images.
result Facial features associated with obstructive sleep apnea can be recognized for diagnosis.

Survey of techniques for diagnosing pediatric sleep apnea from inexpensive data.

problem Diagnosing pediatric sleep apnea from limited and variable data.
method Exploratory data analysis using correlation networks, Mapper, SVD; supervised and unsupervised learning techniques.
result Analysis of various learning techniques applied to pediatric sleep apnea data.

Enhances early risk assessments for pediatric outcomes using contrastive learning.

problem Improving risk assessments in early stages of pediatric development.
method Contrastive multi-modal framework that treats each time window as a distinct modality, training on all available data.
result Consistent improvements in early-stage risk assessments validated on real-world tasks.

New CNN architecture improves pediatric image segmentation by homogenizing pose and size.

problem Challenges in segmenting pediatric images due to pose and size heterogeneity.
method Spatial Transformer Network (STN) for pose and scale invariance, combined with UNet for segmentation.
result Improved pediatric segmentation, especially renal tumor delineation, with accelerated processing.

Study benchmarks contextual bandit algorithms for precision oncology using in vitro data.

problem Designing effective protocols for individual treatment assignment in precision oncology.
method Proposed a benchmark dataset of in vitro drug responses to evaluate contextual bandit algorithms.
result Bayesian bandit algorithms performed better than a rule-based baseline in minimizing regret.

Deep learning predicts asthma ED visits better than traditional methods.

problem Predicting asthma-related ED visits to improve patient management.
method Deep learning (Artificial Neural Networks) compared to Lasso logistic regression.
result Deep learning model (ANN) outperforms traditional Lasso logistic regression (AUC = 0.845 vs. AUC = 0.842).

Deep neural network improves cancer mutation calls with confidence.

problem Improving accuracy and confidence in somatic variant calls from cancer sequencing.
method Deep Bayesian Recurrent Neural Network (RNN) with flexible priors.
result Enhanced confidence in mutation calls without performance degradation.

AI framework uses multi-omics data to personalize cancer treatment suggestions.

problem Leveraging AI for personalized cancer treatment based on complex patient characteristics.
method Modular machine learning framework trained on diverse multi-omics technologies.
result Superior performance in personalized counterfactual treatment suggestions.

A ML-based method reconstructs 3D organ doses from 2D radiographs for pediatric abdominal radiotherapy.

problem Reconstructing detailed 3D dose distributions for childhood cancer survivors using limited 2D radiographs.
method Surrogate-free ML approach using 142 abdominal planning CTs, 300 artificial plans, and evolutionary algorithm.
result Accurate 3D dose reconstructions with MAEs ≤ 1.7 Gy for edge organs, validated on independent dataset.

Generative AI models improve clinical trial data by generating survival outcomes.

problem Generating valid survival outcomes for clinical trials with synthetic data.
method A variational autoencoder (VAE) that jointly generates mixed-type covariates and survival outcomes.
result The method outperforms GAN baselines on fidelity, utility, and privacy metrics.

Deep Bayesian neural networks improve somatic variant calling accuracy.

problem Improving accuracy in pinpointing somatic variants from next-gen sequencing data.
method Deep Bayesian Recurrent Neural Networks (RNNs) for somatic variant calling.
result Deep Bayesian RNNs provide more reliable confidence intervals for variant calls.

We demonstrate a simple strategy to cope with missing data in sequential inputs, addressing the task of multilabel classification of diagnoses given clinical time series. Collected from the pediatric intensive care unit (PICU) at Children's Hospital Los Angeles, our data consists of multivariate time series of observat…

2016-06-13abs ↗pdf ↗

There is growing interest in applying machine learning methods to Electronic Medical Records (EMR). Across different institutions, however, EMR quality can vary widely. This work investigated the impact of this disparity on the performance of three advanced machine learning algorithms: logistic regression, multilayer p…

2017-03-23abs ↗pdf ↗

New method phenotypes sleep apnea patients using time series analysis.

problem Traditional diagnosis of sleep apnea is insufficient for capturing its multi-faceted outcomes.
method Fuzzy clustering in time and frequency domains, and persistent homology for topological analysis.
result Phenotyping patients improves understanding of sleep apnea.

Reinforcement learning algorithms are gaining popularity in fields in which optimal scheduling is important, and oncology is not an exception. The complex and uncertain dynamics of cancer limit the performance of traditional model-based scheduling strategies like Optimal Control. Motivated by the recent success of mode…

2019-04-02abs ↗pdf ↗

auton-survival simplifies survival analysis for healthcare data.

problem Handling censored time-to-event data in healthcare.
method Open-source package for survival regression, adjustment, counterfactual estimation, phenotyping, and treatment effects.
result Demonstrates auton-survival's ability to support complex health and epidemiological questions.

Develops regression trees for estimating cumulative incidence curves in competing risks.

problem Estimating cumulative incidence functions in competing risks settings.
method Uses augmented estimators of the Brier score risk to build and prune regression trees.
result Demonstrates the utility of the proposed methods through simulation studies and real data.

Study uses ML to predict HL survival, outperforming CoxPH.

problem Improving survival prediction for HL patients.
method Compared multiple ML algorithms to CoxPH model.
result ML models outperform CoxPH in predicting HL survival.

Proposes dynamic borrowing method for historical data in clinical trials.

problem Insufficient statistical power in rare and pediatric disease clinical trials.
method Dynamic borrowing method based on frequentist approach using similarity measures.
result Demonstrates usefulness of dynamic borrowing in reanalyzing clinical trial data.

Paper tackles cancer mutation data challenges by creating useful low-dimensional representations.

problem Challenges in analyzing and using cancer mutation data for classification and clustering.
method Flatsomatic: variational autoencoders (VAEs) to create latent representations of somatic profiles.
result VAE embeddings perform better than PCA for clustering and equally well for classification.

The paper tackles distribution-free prediction intervals for multi-source data.

problem Challenges in achieving valid inferences due to distribution shifts and privacy concerns.
method Derives efficient influence functions, incorporates machine learning, and proposes data-adaptive strategies.
result Achieves parametric rates of convergence to nominal coverage probabilities for prediction intervals.

Shared Keyboard design improves phase I clinical trials by borrowing information across doses.

problem Interim decisions based on current dose data may overlook signals from neighboring doses.
method Bayesian model-assisted design using Beta kernel process with kernel-weighted pseudo-counts.
result Significant improvements in identifying maximum tolerated dose and safety.