25% of people who received a liver transplant will go on to develop diabetes within the next 5 years. These thousands of individuals are at 2-fold higher risk of cardiovascular events, graft loss, infections, as well as lower long-term survival. This is partly due to the medication used during and/or after transplant t…
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48 results for “New Onset Diabetes After Transplantation”
New method for finding optimal treatment regimes in medical settings with time-varying unobserved factors.
problem Finding optimal treatment regimes in medical settings with time-varying unobserved factors.
method Extend Dynamic Treatment Regimes (DTRs) to Ambiguous Dynamic Treatment Regimes (ADTRs), connect to Ambiguous Partially Observable Mark Decision Processes (APOMDPs), and develop Reinforcement Learning methods.
result Established theoretical results for learning methods, including consistency and asymptotic normality.
Prediction of disease onset from patient survey and lifestyle data is quickly becoming an important tool for diagnosing a disease before it progresses. In this study, data from the National Health and Nutrition Examination Survey (NHANES) questionnaire is used to predict the onset of type II diabetes. An ensemble model…
Machine learning improves kidney transplant outcomes prediction.
problem Improving prediction of kidney transplant success.
method Random forest machine learning model trained on kidney donor risk index data.
result Random forest predicted 2,148 more successful transplants than the risk index.
Participants enrolled into randomized controlled trials (RCTs) often do not reflect real-world populations. Previous research in how best to translate RCT results to target populations has focused on weighting RCT data to look like the target data. Simulation work, however, has suggested that an outcome model approach …
The burgeoning need for kidney transplantation mandates immediate attention. Mismatch of deceased donor-recipient kidney leads to post-transplant death. To ensure ideal kidney donor-recipient match and minimize post-transplant deaths, the paper develops a prediction model that identifies factors that determine the prob…
Method detects lithium-ion battery knee onset for early warning.
problem Early warning of lithium-ion battery performance changes.
method Temporal dynamics extraction and Matrix Profile anomaly detection.
result Knee onset detected for categorizing battery health.
This paper focuses on a new task, i.e., transplanting a category-and-task-specific neural network to a generic, modular network without strong supervision. We design an functionally interpretable structure for the generic network. Like building LEGO blocks, we teach the generic network a new category by directly transp…
This paper focuses on a new task, i.e., transplanting a category-and-task-specific neural network to a generic, modular network without strong supervision. We design a functionally interpretable structure for the generic network. Like building LEGO blocks, we teach the generic network a new category by directly transpl…
Background: Many authors have described MELD as a predictor of short-term mortality in the liver transplantation waiting list. However MELD score accuracy to predict long term mortality has not been statistically evaluated. Objective: The aim of this study is to analyze the MELD score as well as other variables as a pr…
We study isospectrality for manifolds with mixed Dirichlet-Neumann boundary conditions and express the well-known transplantation method in graph- and representation-theoretic terms. This leads to a characterization of transplantability in terms of monomial relations in finite groups and allows for the generating of ne…
Paper learns data-driven organ matching rules from observational data.
problem Tackles organ transplantation compatibility using observational data.
method Representation learning to cluster donors and apply recipient transformations.
result Model outperforms human experts in predicting transplant outcomes.
Conway's drum quiltsmath.GT
John Conway created pairs of domains that sound the same for a special kind of music.
problem Creating domains that sound the same for a special kind of music.
method Using his theory of quilts, Conway developed pairs of glueing diagrams.
result Conway's pairs of domains are isospectral for the Laplace operator.
Automatic Music Transcription (AMT) is one of the oldest and most well-studied problems in the field of music information retrieval. Within this challenging research field, onset detection and instrument recognition take important places in transcription systems, as they respectively help to determine exact onset times…
Personalized models explain TB treatment outcomes considering patient context.
problem Heterogeneity in TB treatment outcomes due to co-morbidities.
method Multi-task learning approach encoding patient context into personalized models.
result Identifies anemia, age of onset, and HIV as influential for treatment efficacy.
This paper presents the first deep reinforcement learning (DRL) framework to estimate the optimal Dynamic Treatment Regimes from observational medical data. This framework is more flexible and adaptive for high dimensional action and state spaces than existing reinforcement learning methods to model real-life complexit…
Objective: To evaluate unsupervised clustering methods for identifying individual-level behavioral-clinical phenotypes that relate personal biomarkers and behavioral traits in type 2 diabetes (T2DM) self-monitoring data. Materials and Methods: We used hierarchical clustering (HC) to identify groups of meals with simila…
New method interprets deep embeddings for diabetes patient clustering.
problem Interpreting deep embeddings for disease progression.
method Patient clustering approach using deep embeddings.
result Clinically meaningful insights into diabetes progression patterns.
OTRE uses OT to improve retinal images, outperforming existing methods.
problem Improving quality of non-mydriatic retinal images for accurate diagnoses.
method OT theory for image-to-image translation, regularization by enhancing.
result OTRE outperforms state-of-the-art methods on various retinal image tasks.
We say that a germ G of a geometric structure can be transplanted into a manifold M if there is a suitable geometric structure on M which agrees with G on a neighborhood of some point P of M. We show for a wide variety of geometric structures that this transplantation is always possible provided that M does in fact adm…
We advance the state of the art in polyphonic piano music transcription by using a deep convolutional and recurrent neural network which is trained to jointly predict onsets and frames. Our model predicts pitch onset events and then uses those predictions to condition framewise pitch predictions. During inference, we r…
Voice Onset Time (VOT), a key measurement of speech for basic research and applied medical studies, is the time between the onset of a stop burst and the onset of voicing. When the voicing onset precedes burst onset the VOT is negative; if voicing onset follows the burst, it is positive. In this work, we present a deep…
According to the American Diabetes Association(ADA), 30.3 million people in the United States have diabetes, but only 7.2 million may be undiagnosed and unaware of their condition. Type 2 diabetes is usually diagnosed for most patients later on in life whereas the less common Type 1 diabetes is diagnosed early on in li…
This paper provides a ML framework for diabetes prediction and care management.
problem Diabetes prediction and care management challenges in real-world healthcare.
method Illustrates a Machine Learning framework for T2DM prediction and risk stratification.
result ML models align with physician's disease management steps.
Deep neural network predicts diabetic readmission with high accuracy.
problem Predicting 30-day readmission for diabetic patients.
method Categorical embeddings and deep neural network.
result 95.2% accuracy and 97.4% AUROC on diabetic readmission data.
Type 2 diabetes mellitus (T2DM) is a chronic disease that often results in multiple complications. Risk prediction and profiling of T2DM complications is critical for healthcare professionals to design personalized treatment plans for patients in diabetes care for improved outcomes. In this paper, we study the risk of …
Deep learning detects diabetic retinopathy stages from single fundus photos.
problem Early detection of diabetic retinopathy for treatment success.
method Convolutional neural networks (CNN) for automatic stage detection.
result Sensitivity and specificity of 0.99 on APTOS 2019 Blindness Detection Dataset.
Diabetes is a globally prevalent disease that can cause visible microvascular complications such as diabetic retinopathy and macular edema in the human eye retina, the images of which are today used for manual disease screening. This labor-intensive task could greatly benefit from automatic detection using deep learnin…
Health professionals can use natural language processing (NLP) technologies when reviewing electronic health records (EHR). Machine learning free-text classifiers can help them identify problems and make critical decisions. We aim to develop deep learning neural network algorithms that identify EHR progress notes perta…
CopulaSMOTE addresses class imbalance in diabetes prediction models.
problem Class imbalance in diabetes prediction models, especially with fewer confirmed cases.
method Copula-based oversampling approach that models joint dependence structure.
result CopulaSMOTE improves minority-class recovery in larger diabetes datasets.
Importance sampling is often used in machine learning when training and testing data come from different distributions. In this paper we propose a new variant of importance sampling that can reduce the variance of importance sampling-based estimates by orders of magnitude when the supports of the training and testing d…
New model predicts blood glucose in diabetics with improved accuracy.
problem Forecasting blood glucose in type 1 diabetics with high accuracy.
method Integrates machine learning with existing biomedical model to capture time-varying dynamics.
result Improved long-term forecasting of blood glucose up to 6 hours.
Method learns evolving policies in healthcare contexts.
problem Understanding non-stationary behavior in evolving decision-making processes.
method Inverse Contextual Bandits (ICB) approach for learning interpretable representations of non-stationary behavior.
result Demonstrated applicability and accuracy of ICB method in liver transplantation policies.
Reinforcement Learning improves insulin bolus decisions for type-I diabetes patients.
problem Optimal insulin bolus decisions for type-I diabetes patients are not well-established.
method Applied Reinforcement Learning to simulated T1DM data.
result Optimal bolus rule differs from standard advisors and can prevent hypoglycemia.
Novel framework detects CKD in diabetic patients using sparse EHR representations.
problem Early detection of CKD in diabetic patients.
method Sparse longitudinal representations of EHR data.
result Proposed model achieves higher predictive performance than baselines.
Machine learning detects subtle glucose changes for early diabetes diagnosis.
problem Challenging early-stage diabetes diagnosis due to subtle glucose changes.
method Applied machine learning to synthetic glucose profiles generated by a biophysical model.
result High accuracy (above 85%) in detecting insulin resistance using various neural networks.
Stocks of more resilient firms outperformed during the pandemic, reflecting disaster risk.
problem The impact of social distancing on firms' operations and stock performance.
method Cross-sectional analysis of firms' resilience and stock performance, controlling for risk factors.
result Stocks of more resilient firms are expected to yield significantly lower returns than less resilient ones, reflecting disaster risk.
Social media based digital epidemiology has the potential to support faster response and deeper understanding of public health related threats. This study proposes a new framework to analyze unstructured health related textual data via Twitter users' post (tweets) to characterize the negative health sentiments and non-…
The paper examines how calibration affects the interpretability of ML models in diabetes screening.
problem Interpreting complex ML models in healthcare, especially in diabetes screening.
method Examined the impact of model calibration on interpretability using three visualization techniques.
result Calibrated models provide clearer cause-effect relationships in ML predictions.
Paper develops NN models for diabetes screening using NHANES data.
problem Developing accurate predictive models for diabetes in diverse populations.
method Proposes a neural network framework with survey weights, uncertainty quantification.
result Robust risk score models for diabetes in US population.
Diabetes mellitus is a common disease of human body caused by a group of metabolic disorders where the sugar levels over a prolonged period is very high. It affects different organs of the human body which thus harm a large number of the body's system, in particular the blood veins and nerves. Early prediction in such …
Artificial Intelligence for Diabetes Case Management: The Intersection of Physical and Mental Healthq-bio.QM
Diabetes is a major public health problem in the United States, affecting roughly 30 million people. Diabetes complications, along with the mental health comorbidities that often co-occur with them, are major drivers of high healthcare costs, poor outcomes, and reduced treatment adherence in diabetes. Here, we evaluate…
Social media provide a platform for users to express their opinions and share information. Understanding public health opinions on social media, such as Twitter, offers a unique approach to characterizing common health issues such as diabetes, diet, exercise, and obesity (DDEO), however, collecting and analyzing a larg…
HAD-Net forecasts glucose levels with insights into insulin and carbs diffusion.
problem Inaccurate predictions in glucose level forecasting without context understanding.
method Hybrid model combining deep learning and physiological models, using recurrent attention network.
result Achieves competitive performance in glucose level forecasting with plausible diffusion insights.
Deep learning has been successfully applied to a variety of image classification tasks. There has been keen interest to apply deep learning in the medical domain, particularly specialties that heavily utilize imaging, such as ophthalmology. One issue that may hinder application of deep learning to the medical domain is…
With continuous glucose monitoring (CGM), data-driven models on blood glucose prediction have been shown to be effective in related work. However, such (CGM) systems are not always available, e.g., for a patient at home. In this work, we conduct a study on 9 patients and examine the online predictability of data-driven…
A method models continuous-time glucose distributions in children with diabetes.
problem Capturing subtle temporal changes in glucose distributions.
method Probabilistic framework using Gaussian mixtures and neural ODEs.
result Detects treatment-related improvements in glucose dynamics.
Local Causal Structure Learning and its Discovery Between Type 2 Diabetes and Bone Mineral Densityq-bio.QM
A new algorithm discovers causal factors between T2DM and bone mineral density.
problem Discovering causal factors between T2DM and bone mineral density from clinical data.
method Prior-Knowledge-driven local Causal structure Learning (PKCL) algorithm.
result PKCL achieves more reliable results without long-standing medical experiments.