New framework for managing medical risks using convex responses.
arXiv research
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ChatGPT's medical response accuracy is 56%, but studies vary widely.
Proposes a deep neural network approach for image response regression.
Exploring a new method to explain AI models in medical devices.
Proposes DeepSDRF for continuous treatment recommendation from clinical survival data.
Objective: Predict individual septic children's personalized physiologic responses to vasoactive titrations by training a Recurrent Neural Network (RNN) using EMR data. Materials and Methods: This study retrospectively analyzed EMR of patients admitted to a pediatric ICU from 2009 to 2017. Data included charted time se…
Estimation of response functions is an important task in dynamic medical imaging. This task arises for example in dynamic renal scintigraphy, where impulse response or retention functions are estimated, or in functional magnetic resonance imaging where hemodynamic response functions are required. These functions can no…
CASCADE improves uncertainty communication in Parkinson's disease medication management.
Develops a two-stage conformal prediction method for Parkinson's disease medication needs.
Proposes using external data to improve predictions in medical applications with limited samples.
This Perspective provides examples of current and future applications of deep learning in pharmacogenomics, including: (1) identification of novel regulatory variants located in noncoding domains and their function as applied to pharmacoepigenomics; (2) patient stratification from medical records; and (3) prediction of…
Framework extracts symptoms from EHRs for rapid disease outbreak detection.
Differentially private geodesic regression for non-Euclidean data.
New methods protect privacy while providing accurate prediction sets.
New method estimates treatment effects over time with unobserved confounders.
New method uses probabilistic independence to discover disease signatures from medical records.
Multi-output Gaussian processes (GPs) are a flexible Bayesian nonparametric framework that has proven useful in jointly modeling the physiological states of patients in medical time series data. However, capturing the short-term effects of drugs and therapeutic interventions on patient physiological state remains chall…
The application of deep learning to build accurate predictive models from functional neuroimaging data is often hindered by limited dataset sizes. Though data augmentation can help mitigate such training obstacles, most data augmentation methods have been developed for natural images as in computer vision tasks such as…
Electronic medical records (EMRs) supports the development of machine learning algorithms for predicting disease incidence, patient response to treatment, and other healthcare events. But insofar most algorithms have been centralized, taking little account of the decentralized, non-identically independently distributed…
Accurately predicting when and where ambulance call-outs occur can reduce response times and ensure the patient receives urgent care sooner. Here we present a novel method for ambulance demand prediction using Gaussian process regression (GPR) in time and geographic space. The method exhibits superior accuracy to MEDIC…
Improves medication name inference for telemedicine and conversational agents.
Tensors are becoming prevalent in modern applications such as medical imaging and digital marketing. In this paper, we propose a sparse tensor additive regression (STAR) that models a scalar response as a flexible nonparametric function of tensor covariates. The proposed model effectively exploits the sparse and low-ra…
The treatment effects of medications play a key role in guiding medical prescriptions. They are usually assessed with randomized controlled trials (RCTs), which are expensive. Recently, large-scale electronic health records (EHRs) have become available, opening up new opportunities for more cost-effective assessments. …
Two large medical dialogue datasets for improving healthcare.
Proposes guidelines for developing medical AI products.
Three approaches learn personalized treatment policies for UTI patients.
CAST models time-varying treatment effects in cancer patients.
As machine learning algorithms are increasingly applied to high impact yet high risk tasks, such as medical diagnosis or autonomous driving, it is critical that researchers can explain how such algorithms arrived at their predictions. In recent years, a number of image saliency methods have been developed to summarize …
Classical scalar-response regression methods treat covariates as a vector and estimate a corresponding vector of regression coefficients. In medical applications, however, regressors are often in a form of multi-dimensional arrays. For example, one may be interested in using MRI imaging to identify which brain regions …
The medical field stands to see significant benefits from the recent advances in deep learning. Knowing the uncertainty in the decision made by any machine learning algorithm is of utmost importance for medical practitioners. This study demonstrates the utility of using Bayesian LSTMs for classification of medical time…
There has been increasing interest in modelling survival data using deep learning methods in medical research. Current approaches have focused on designing special cost functions to handle censored survival data. We propose a very different method with two steps. In the first step, we transform each subject's survival …
Segmentation of anatomical structures and pathologies is inherently ambiguous. For instance, structure borders may not be clearly visible or different experts may have different styles of annotating. The majority of current state-of-the-art methods do not account for such ambiguities but rather learn a single mapping f…
This paper benchmarks privacy-preserving machine learning on medical images.
It is crucial to provide compatible treatment schemes for a disease according to various symptoms at different stages. However, most classification methods might be ineffective in accurately classifying a disease that holds the characteristics of multiple treatment stages, various symptoms, and multi-pathogenesis. More…
Laboratory testing and medication prescription are two of the most important routines in daily clinical practice. Developing an artificial intelligence system that can automatically make lab test imputations and medication recommendations can save costs on potentially redundant lab tests and inform physicians of a more…
Enhanced conformal methods improve validity of LLM outputs.
Machine learning constructs problem-based medical records from electronic health records.
Sepsis is a poorly understood and potentially life-threatening complication that can occur as a result of infection. Early detection and treatment improves patient outcomes, and as such it poses an important challenge in medicine. In this work, we develop a flexible classifier that leverages streaming lab results, vita…
AI generates a sequence of death causes from hospital records.
A treatment regime is a function that maps individual patient information to a recommended treatment, hence explicitly incorporating the heterogeneity in need for treatment across individuals. Patient responses are dichotomous and can be predicted through an unknown relationship that depends on the patient information …
SAVAE uses deep learning for survival analysis, improving model performance and interpretability.
Paper defines feature impact and importance from data, not models.
Enhances medical code predictions for multi-morbidity patients using text classification.
Paper detects bias in AI medical models using CART.
The rate at which medical questions are asked online far exceeds the capacity of qualified people to answer them, and many of these questions are not unique. Identifying same-question pairs could enable questions to be answered more effectively. While many research efforts have focused on the problem of general questio…
Representation learning (RL) plays an important role in extracting proper representations from complex medical data for various analyzing tasks, such as patient grouping, clinical endpoint prediction and medication recommendation. Medical data can be divided into two typical categories, outpatient and inpatient, that h…
This study applies neural models to automatically recognize medical entities from natural language.
Survey of deep learning methods for medical anomaly detection.