It becomes increasingly popular to perform mediation analysis for complex data from sophisticated experimental studies. In this paper, we present Granger Mediation Analysis (GMA), a new framework for causal mediation analysis of multiple time series. This framework is motivated by a functional magnetic resonance imagin…
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48 results for “Mediating Variable”
New method handles indirect mediators in CMA for complex scenarios.
problem Handling indirect and multi-dimensional mediators in causal mediation analysis.
method Identifiable Variational Autoencoder (iVAE) architecture for multi-dimensional, indirectly observed mediators.
result Accurate estimation of direct and mediated effects in synthetic and semi-synthetic experiments.
New method stabilizes IF-based estimators for causal mediation analysis with continuous mediators.
problem Stability issues in IF-based estimators for continuous mediators.
method Nonparametric weighted balancing method to estimate nuisance functions.
result Significant reductions in bias and variance compared to existing methods.
MediEncoder: Nonlinear Representation Learning for High-Dimensional Causal Mediation Analysisstat.ME
MediEncoder learns nonlinear representations for causal mediation analysis.
problem High-dimensional noisy covariates and mediators in biomedical studies.
method Coupled encoder-decoder architecture with cross-factor network.
result Improves estimation accuracy in high-dimensional causal mediation analysis.
Unified framework for estimating indirect effects in observational studies with unmeasured confounding.
problem Challenges in evaluating indirect effects due to unmeasured confounding and unethical exposures.
method Developed a unified identification and estimation framework using proximal causal inference.
result Unified identification and estimation of PIIE and causal effect of an intervening variable in settings with pervasive unmeasured confounding.
New method analyzes complex multivariate pathways in high-dimensional data.
problem High-dimensional mediation analysis of multivariate exposures, mediators, and outcomes.
method Simultaneous variable selection, indirect effect matrix estimation, and prediction of multivariate outcomes.
result Identifies biologically interpretable genetic-neural-cognitive pathways.
PESCAL uses mediators to learn from confounded offline data.
problem Learning from confounded observational data in reinforcement learning.
method PESCAL uses mediator variables and the pessimistic principle to address confounding bias and distributional shift.
result It is sufficient to learn a lower bound of the mediator distribution function to mitigate distributional shift.
A new RL framework evaluates dynamic mediation effects over time.
problem Dynamic mediation effects in sequentially assigned treatments.
method Reinforcement Learning framework for decomposition and estimation of causal effects.
result Superior performance demonstrated through numerical studies and real data analysis.
Study compares estimators for causal mediation analysis with multiple mediators.
problem Estimating causal effects through multiple mediators in observational studies.
method Parametric and non-parametric estimators, including multiply robust and double machine learning approaches.
result Advanced estimators perform well across various settings and real data.
New method learns functions without paired data using mediating variables.
problem Learning functions without paired input-output data.
method Mediated Uncoupled Learning: Predicting to approximate .
result Statistical consistency and error bounds of the proposed method.
New methods estimate causal effects through mediators, handling confounding without strict assumptions.
problem Estimating causal effects through mediators while accounting for unmeasured confounding.
method Developed four nonparametric identification strategies using proximal confounding bridge functions, efficient influence function, and quadruply robust estimator. Proposed proximal debiased machine learning approach for high-dimensional nuisance parameters.
result Achieved -consistency and asymptotic normality for path-specific effect estimation.
Proposes new method to handle hidden confounders in causal mediation analysis.
problem Break down total effect of treatment on outcome through different causal pathways.
method Combines proxy strategies and deep learning to uncover latent variables and estimate causal effects.
result Validated effectiveness of the proposed method for causal fairness analysis.
The paper compares and optimizes estimators for treatment effects with observed confounders and mediators.
problem Estimating treatment effects with observed confounders and mediators.
method Investigates the linear Gaussian causal model, compares and optimizes estimators, and combines datasets.
result An optimal estimator outperforms the backdoor and frontdoor estimators by an unbounded constant factor.
We consider the problem of identifying intermediate variables (or mediators) that regulate the effect of a treatment on a response variable. While there has been significant research on this classical topic, little work has been done when the set of potential mediators is high-dimensional (HD). A further complication a…
Summary statistics of genome-wide association studies (GWAS) teach causal relationship between millions of genetic markers and tens and thousands of phenotypes. However, underlying biological mechanisms are yet to be elucidated. We can achieve necessary interpretation of GWAS in a causal mediation framework, looking to…
Proximal Mediation Analysis with Hidden Recanting Witnesses
problem Identifying path-specific effects in mediation analysis when recanting witnesses are unknown
method Proximal causal inference and semiparametric inference framework
result Developed three novel identification strategies and a semiparametric inference framework
Study decomposes racial healthcare disparities via shifts in mediator distributions.
problem Racial disparities in healthcare expenditures and their underlying drivers.
method Framework decomposing disparities into mediator distribution shifts and residual components, using MEPS data.
result Substantial disparities persist even when mediators are equalized, suggesting unmeasured or structural factors.
New method reduces bias in estimating causal effects from discretized variables.
problem Bias in estimating causal effects from discretized continuous variables.
method Proposes a bias-reduced functional that evaluates outcome regression at within-bin conditional means.
result Demonstrates substantial bias reduction and near-nominal confidence interval coverage.
Extends causal inference to hidden mediators with proxies.
problem Identifying causal effects with hidden mediators and error-prone proxies.
method Established causal hidden mediation analysis and hidden front-door criterion.
result Identification of population intervention indirect effect possible with hidden mediators.
Study introduces a new method to estimate causal mediation with multiple mediators.
problem Estimating causal effects with multiple mediators and confounders.
method Simulates potential outcomes using parametric and nonparametric models.
result General approach to estimating various causal mediation quantities.
Maturation Trajectories of Cortical Resting-State Networks Depend on the Mediating Frequency Bandq-bio.NC
The functional significance of resting state networks and their abnormal manifestations in psychiatric disorders are firmly established, as is the importance of the cortical rhythms in mediating these networks. Resting state networks are known to undergo substantial reorganization from childhood to adulthood, but wheth…
Paper proposes a machine learning-based method for estimating mediation effects.
problem Challenges in estimating mediation effects with multiple, continuous mediators.
method Developed a one-step estimation algorithm using machine learning and Riesz learning.
result Proposed method can estimate mediation effects from just two statistical estimands.
In many scientific studies, it becomes increasingly important to delineate the causal pathways through a large number of mediators, such as genetic and brain mediators. Structural equation modeling (SEM) is a popular technique to estimate the pathway effects, commonly expressed as products of coefficients. However, it …
Identification and multiply robust estimation in causal mediation analysis across principal stratastat.ME
The paper addresses causal mediation analysis with post-treatment events, proposing robust estimators and efficient methods.
problem Assessing causal mediation in the presence of post-treatment events like noncompliance or clinical events.
method Identifies natural mediation effects for entire populations and principal strata, derives efficient influence functions, and proposes multiply robust estimators.
result Multiply robust estimators are consistent under four types of misspecifications and efficient when all models are correct.
A new DML method for continuous treatments uncovers causal mediation effects.
problem Estimating causal mediation effects with continuous treatments.
method Double machine learning (DML) algorithm using kernel-based doubly robust moment function.
result Asymptotic normality with nonparametric convergence rate for estimating mediated response curve.
Tests whether a treatment's effect is fully mediated by observed outcomes and identifies causal mechanisms.
problem Understanding how a treatment affects an outcome through intermediate variables.
method Proposes a test to evaluate full mediation and causal mechanism identification, extending to non-randomly assigned treatments.
result A conditionally random treatment is conditionally independent of the outcome given mediators and covariates if full mediation and causal mechanism identification hold.
A method combines deep learning and G-estimation for causal mediation analysis.
problem Estimating structural mediation parameters under unmeasured confounding.
method UNIT method using TARNet for representation learning and G-estimation.
result Improved precision of structural parameter estimator through better representation learning.
Proposes estimators for complex dose-response curves using kernel methods.
problem Estimating complex dose-response curves with continuous treatments, mediators, and covariates.
method Kernel ridge regression with sequential kernel embedding technique.
result Simple estimators for mediated and time-varying dose response curves with nonasymptotic uniform rates.
DCMA uses generative models to analyze treatment effects on entire outcome distributions.
problem Traditional mediation analysis focuses on summary contrasts, missing complex distributional changes.
method DCMA learns conditional generative models for mediators and outcome, reconstructing interventional distributions via Monte Carlo simulation.
result DCMA captures both summary effects and rich distributional contrasts like energy distance and Wasserstein distance.
DCMA uses generative models to analyze complex treatment effects on outcome distributions.
problem Analyzing complex and nonlinear causal mechanisms through outcome-level summary contrasts.
method Generative learning framework for identifying and estimating treatment effects on entire outcome distributions.
result Reconstructs interventional outcome distributions via Monte Carlo forward simulation, capturing both summary and distributional contrasts.
A new method for identifying the best arm in multi-armed bandits with mediator feedback.
problem Sequential decision-making with unknown mediator policies.
method Best-arm identification under mediators' feedback (BAI-MF) with statistical lower bound and sequential decision-making strategy.
result The proposed algorithm matches the lower bound on sample complexity for identifying the best arm.
Doubly Robust Estimation of Direct and Indirect Quantile Treatment Effects with Machine Learningecon.EM
Estimates causal effects using machine learning for binary treatment and mediator.
problem Estimating direct and indirect quantile treatment effects under selection-on-observables.
method Double/debiased machine learning estimators based on efficient score functions.
result Uniform consistency and asymptotic normality of effect estimators.
Develops tools to decompose spurious variations in causal models.
problem Understanding and decomposing spurious variations in causal relationships.
method Formal tools for decomposing spurious effects in Markovian and Semi-Markovian models.
result First results on non-parametric decomposition of spurious effects and sufficient conditions for identification.
DeepMed uses DNNs to estimate causal mediation effects without sparsity constraints.
problem Estimating Natural Direct and Indirect Effects in mediation analysis.
method DeepMed employs deep neural networks to cross-fit infinite-dimensional nuisance functions.
result DeepMed achieves semiparametric efficiency bound and adapts to low-dimensional nuisance structures.
M-learner estimates treatment effects in mediation models with subgroup identification.
problem Estimating heterogeneous treatment effects in mediation models.
method Four-step procedure: compute conditional effects, construct distance matrix, apply tSNE and K-means clustering, refine clusters.
result Validates robustness and effectiveness in real-world dataset.
New methods identify causal effects without needing complete proxy variables.
problem Identifying causal effects in the presence of unmeasured confounders.
method Partial identification methods that do not require completeness of proxy variables.
result Obtain bounds on causal effects using available proxy variables.
Online Decision Mediationstat.ML
An assistant learns to mediate decisions between humans and experts, balancing risk and learning.
problem Learning to mediate decisions between imperfect humans and expert knowledge.
method Formalizes online decision mediation, proposes a policy to balance immediate loss and future generalization.
result Consistent gains over benchmarks in decision-making performance.
Collective phenomena with universal properties have been observed in many complex systems with a large number of components. Here we present a microscopic model of the emergence of scaling behavior in such systems, where the interaction dynamics between individual components is mediated by a global variable making the …
A new algorithm uses IVs to learn optimal policies from observational data.
problem Learning optimal policies from unobserved variable confounded data.
method IV-aided Value Iteration (IVVI) algorithm based on conditional moment restrictions.
result First provably efficient algorithm for instrument-aided offline RL.
The paper identifies the best treatment to maximize NDPO, a key outcome in causal mediation analysis.
problem Identifying the treatment that maximizes the expected natural direct potential outcome (NDPO) in causal mediation analysis.
method Developed a fixed-confidence best-arm identification (BAI) algorithm based on the Track-and-Stop (TaS) framework, using a cutting-set method to solve a semi-infinite optimization problem.
result The proposed algorithm achieves sample-efficient identification with a high-probability correctness guarantee and asymptotic optimality.
RANDomized-exploration policy Optimization via Multiple Importance Sampling with Truncation (RANDOMIST) for PO with mediator feedback.
problem Policy Optimization in continuous control tasks.
method RANDomized-exploration policy Optimization via Multiple Importance Sampling with Truncation (RANDOMIST) for regret minimization in PO.
result Achieving constant regret under certain circumstances in PO with mediator feedback.
Strategic brokers exploit private information in broker-mediated markets, affecting informed traders' performance.
problem Strategic interactions and information leakage in broker-mediated markets.
method Study of strategic trading behavior and information leakage in a broker-mediated market.
result Brokers hold a strategic advantage over informed traders due to information leakage in trading flows.
New methods for estimating complex causal effects in econometrics.
problem Estimating causal parameters in short panel data models using nested nonparametric instrumental variable regression.
method Introducing techniques to limit ill-posedness in nested NPIV, providing explicit mean square rates and efficient inference.
result Explicit mean square rates for nested NPIV and efficient inference for causal parameters.
New algorithm bounds regret in mediator feedback bandit problems.
problem Mediator feedback bandit game with policy sets.
method Adopting EXP4 algorithm, new regret bounds based on policy set capacity.
result Nearly-matching lower bounds for policy set families.
Proposes a new estimator for causal mediation with continuous treatments.
problem Estimation of direct and indirect effects with continuous treatments.
method Kernel smoothing approach with cross-fitting for non-parametric estimation.
result Multiply robust and asymptotically normal estimator for continuous treatments.
We study the problem of discovering the simplest latent variable that can make two observed discrete variables conditionally independent. The minimum entropy required for such a latent is known as common entropy in information theory. We extend this notion to Renyi common entropy by minimizing the Renyi entropy of the …
Proposes a new training algorithm for zero-sum games to avoid convergence issues.
problem Gradient-based training leads to weak convergence and cyclic dynamics in zero-sum architectures.
method Follow the perturbed leader algorithm with neural mediating agent.
result Guarantees convergence to mixed Nash equilibrium without cyclic behaviors.
This paper models financial contagion with endogenously determined market liquidity.
problem Financial contagion and its impact on market liquidity during price drops.
method Developed a joint clearing system for interbank payments, asset prices, and market liquidity, with endogenous market capacity.
result Endogenous market liquidity significantly affects system risk during financial contagion.