arXiv research

Study re-evaluates MIMIC-III codes, finding many are under-coded.

Purveyors of malicious network attacks continue to increase the complexity and the sophistication of their techniques, and their ability to evade detection continues to improve as well. Hence, intrusion detection systems must also evolve to meet these increasingly challenging threats. Machine learning is often used to …

Background: Elderly patients with MODS have high risk of death and poor prognosis. The performance of current scoring systems assessing the severity of MODS and its mortality remains unsatisfactory. This study aims to develop an interpretable and generalizable model for early mortality prediction in elderly patients wi…

Scoping review and benchmarking of synthetic EHR data generation methods.

Electronic health records (EHR) systems contain vast amounts of medical information about patients. These data can be used to train machine learning models that can predict health status, as well as to help prevent future diseases or disabilities. However, getting patients' medical data to obtain well-trained machine l…

Automated medical prognosis has gained interest as artificial intelligence evolves and the potential for computer-aided medicine becomes evident. Nevertheless, it is challenging to design an effective system that, given a patient's medical history, is able to predict probable future conditions. Previous works, mostly c…

Study evaluates federated learning with differential privacy on MIMIC-III, improving model performance with careful parameter tuning.

Deep learning models (aka Deep Neural Networks) have revolutionized many fields including computer vision, natural language processing, speech recognition, and is being increasingly used in clinical healthcare applications. However, few works exist which have benchmarked the performance of the deep learning models with…

Given independent samples generated from the joint distribution $p(\mathbf{x},\mathbf{y},\mathbf{z})$, we study the problem of Conditional Independence (CI-Testing), i.e., whether the joint equals the CI distribution $p^{CI}(\mathbf{x},\mathbf{y},\mathbf{z})= p(\mathbf{z}) p(\mathbf{y}|\mathbf{z})p(\mathbf{x}|\mathbf{z…

Time series data are prevalent in electronic health records, mostly in the form of physiological parameters such as vital signs and lab tests. The patterns of these values may be significant indicators of patients' clinical states and there might be patterns that are unknown to clinicians but are highly predictive of s…

As state-of-the-art deep neural networks are deployed at the core of more advanced Al-based products and services, the incentive for copying them (i.e., their intellectual properties) by rival adversaries is expected to increase considerably over time. The best way to extract or steal knowledge from such networks is by…

Machine learning for healthcare often trains models on de-identified datasets with randomly-shifted calendar dates, ignoring the fact that data were generated under hospital operation practices that change over time. These changing practices induce definitive changes in observed data which confound evaluations which do…

Objective: Patient notes in electronic health records (EHRs) may contain critical information for medical investigations. However, the vast majority of medical investigators can only access de-identified notes, in order to protect the confidentiality of patients. In the United States, the Health Insurance Portability a…

Robust machine learning relies on access to data that can be used with standardized frameworks in important tasks and the ability to develop models whose performance can be reasonably reproduced. In machine learning for healthcare, the community faces reproducibility challenges due to a lack of publicly accessible data…

In this paper, a Wide Learning architecture is proposed that attempts to automate the feature engineering portion of the machine learning (ML) pipeline. Feature engineering is widely considered as the most time consuming and expert knowledge demanding portion of any ML task. The proposed feature recommendation approach…

PIN models feature interactions using a neural network that mimics decision trees.

Paper simplifies complex sports analytics models for better understanding.

The paper tackles ICU discharge strategies by evaluating optimal stopping scenarios.

Study benchmarks uncertainty quantification in chest X-ray classification.

X-CAL improves survival model calibration without sacrificing predictive power.

New model predicts ICU patient stays more accurately.

We study multiple rule-based and machine learning (ML) models for sepsis detection. We report the first neural network detection and prediction results on three categories of sepsis. We have used the retrospective Medical Information Mart for Intensive Care (MIMIC)-III dataset, restricted to intensive care unit (ICU) p…

Trends in terrestrial temperature variability are perhaps more relevant for species viability than trends in mean temperature. In this paper, we develop methodology for estimating such trends using multi-resolution climate data from polar orbiting weather satellites. We derive two novel algorithms for computation that …

We consider technology-assisted mimicry attacks in the context of automatic speaker verification (ASV). We use ASV itself to select targeted speakers to be attacked by human-based mimicry. We recorded 6 naive mimics for whom we select target celebrities from VoxCeleb1 and VoxCeleb2 corpora (7,365 potential targets) usi…

Self-paced learning (SPL) mimics the cognitive process of humans, who generally learn from easy samples to hard ones. One key issue in SPL is the training process required for each instance weight depends on the other samples and thus cannot easily be run in a distributed manner in a large-scale dataset. In this paper,…

GRU-D detects age-specific missing patterns in vital signs.

New method improves compatibility of risk stratification models without sacrificing accuracy.

Generating datasets that "look like" given real ones is an interesting tasks for healthcare applications of ML and many other fields of science and engineering. In this paper we propose a new method of general application to binary datasets based on a method for learning the parameters of a latent variable moment that …

Abbreviation disambiguation is important for automated clinical note processing due to the frequent use of abbreviations in clinical settings. Current models for automated abbreviation disambiguation are restricted by the scarcity and imbalance of labeled training data, decreasing their generalizability to orthogonal s…

Deep Reinforcement Learning (DRL) has achieved impressive success in many applications. A key component of many DRL models is a neural network representing a Q function, to estimate the expected cumulative reward following a state-action pair. The Q function neural network contains a lot of implicit knowledge about the…

Framework improves clinical timeline reconstruction from text and tables.

While deep learning models become more widespread, their ability to handle unseen data and generalize for any scenario is yet to be challenged. In medical imaging, there is a high heterogeneity of distributions among images based on the equipment that generates them and their parametrization. This heterogeneity trigger…

We propose a practical approach based on federated learning to solve out-of-domain issues with continuously running embedded speech-based models such as wake word detectors. We conduct an extensive empirical study of the federated averaging algorithm for the "Hey Snips" wake word based on a crowdsourced dataset that mi…

One key use of k-means clustering is to identify cluster prototypes which can serve as representative points for a dataset. However, a drawback of using k-means cluster centers as representative points is that such points distort the distribution of the underlying data. This can be highly disadvantageous in problems wh…

The MIMIC-CXR dataset is (to date) the largest released chest x-ray dataset consisting of 473,064 chest x-rays and 206,574 radiology reports collected from 63,478 patients. We present the results of training and evaluating a collection of deep convolutional neural networks on this dataset to recognize multiple common t…

CLIP dataset helps extract action items from hospital discharge notes.

Mimetic initialization improves Transformer training on small datasets.

dnamite simplifies NAMs for feature selection and survival analysis.

Sepsis is a life-threatening condition caused by the body's response to an infection. In order to treat patients with sepsis, physicians must control varying dosages of various antibiotics, fluids, and vasopressors based on a large number of variables in an emergency setting. In this project we employ a "world model" m…

We present a method to develop a Hodge theory for tangential cohomology of foliations by mimicing Witten's approach to ordinary Morse theory by perturbations of the Laplacian

More accurate machine learning models often demand more computation and memory at test time, making them difficult to deploy on CPU- or memory-constrained devices. Teacher-student compression (TSC), also known as distillation, alleviates this burden by training a less expensive student model to mimic the expensive teac…

k-Nearest Neighbors is one of the most fundamental but effective classification models. In this paper, we propose two families of models built on a sequence to sequence model and a memory network model to mimic the k-Nearest Neighbors model, which generate a sequence of labels, a sequence of out-of-sample feature vecto…

Electronic health records (EHR) are rich heterogeneous collection of patient health information, whose broad adoption provides great opportunities for systematic health data mining. However, heterogeneous EHR data types and biased ascertainment impose computational challenges. Here, we present mixEHR, an unsupervised g…

ButterflyFlow uses butterfly matrices for efficient invertible layers in normalizing flows.

Gaussian state space models have been used for decades as generative models of sequential data. They admit an intuitive probabilistic interpretation, have a simple functional form, and enjoy widespread adoption. We introduce a unified algorithm to efficiently learn a broad class of linear and non-linear state space mod…

Outlier detection has received special attention in various fields, mainly for those dealing with machine learning and artificial intelligence. As strong outliers, anomalies are divided into the point, contextual and collective outliers. The most important challenges in outlier detection include the thin boundary betwe…

Heart disease remains the leading cause of death in the United States. Compared with risk assessment guidelines that require manual calculation of scores, machine learning-based prediction for disease outcomes such as mortality can be utilized to save time and improve prediction accuracy. This study built and evaluated…

When training clinical prediction models from electronic health records (EHRs), a key concern should be a model's ability to sustain performance over time when deployed, even as care practices, database systems, and population demographics evolve. Due to de-identification requirements, however, current experimental pra…