KM-GPT automates IPD reconstruction from KM plots with high accuracy and scalability.
problem Manual digitization of IPD from KM plots is error-prone and lacks scalability.
method KM-GPT integrates advanced image preprocessing, multi-modal reasoning, and iterative reconstruction algorithms.
result KM-GPT generates high-quality IPD without manual input or intervention, achieving superior accuracy.
This paper addresses issues with the Brier score in administrative censoring scenarios.
problem Problems with the Brier score in administrative censoring scenarios.
method Proposes an alternative Brier score for administratively censored data.
result The administrative Brier score is valid even when censoring times can be identified from covariates.
Study predicts colorectal polyp recurrence using medical records and statistical models.
problem Identifying patient characteristics influencing colorectal polyp recurrence.
method Natural language processing for extracting polyp characteristics, Kaplan-Meier curves, Cox proportional hazards modeling, random survival forest models.
result Polyp size, number, location, and patient smoking status significantly influence recurrence risk.
Securely analyzes survival data across multiple institutions without revealing individual patient records.
problem Privacy concerns in federated survival analysis of health data.
method Multiparty homomorphic encryption for approximate floating-point computation and encrypted aggregation.
result Privacy-preserving federated Kaplan--Meier survival analysis with high fidelity and predictable overhead.
New methods estimate survival functions with time-varying covariates.
problem Estimating survival functions with time-varying covariates.
method Generalized conditional inference and relative risk forests, adapted transformation forest.
result Proposed methods outperform traditional models in estimating survival functions.
We consider the classic supervised learning problem, where a continuous non-negative random label Y (i.e. a random duration) is to be predicted based upon observing a random vector X valued in Rd with d≥1 by means of a regression rule with minimum least square error. In various applications, rangi…
We establish the first nonasymptotic error bounds for Kaplan-Meier-based nearest neighbor and kernel survival probability estimators where feature vectors reside in metric spaces. Our bounds imply rates of strong consistency for these nonparametric estimators and, up to a log factor, match an existing lower bound for c…
SDPM models survival analysis without parametric assumptions, achieving competitive performance.
problem Estimating survival distributions from censored data with flexibility and accuracy.
method Generative model using denoising diffusion, avoiding parametric assumptions and discretization.
result SDPM achieves competitive predictive performance across various metrics.
This monograph introduces deep learning models for predicting time-to-event outcomes.
problem Predicting critical events and their timing from time series data.
method Neural networks and deep learning models for survival analysis.
result Improved accuracy in predicting time-to-event outcomes using deep learning.
Survival function estimation is used in many disciplines, but it is most common in medical analytics in the form of the Kaplan-Meier estimator. Sensitive data (patient records) is used in the estimation without any explicit control on the information leakage, which is a significant privacy concern. We propose a first d…
We propose a method for detection and prediction of native and synthetic iceberg orders on Chicago Mercantile Exchange. Native (managed by the exchange) icebergs are detected using discrepancies between the resting volume of an order and the actual trade size as indicated by trade summary messages, as well as by tracki…
Survival analysis is a type of semi-supervised ranking task where the target output (the survival time) is often right-censored. Utilizing this information is a challenge because it is not obvious how to correctly incorporate these censored examples into a model. We study how three categories of loss functions, namely …
New estimator for survival function with missing not at random censoring indicators.
problem Estimating survival function with missing not at random censoring indicators.
method Proposes a new estimator based on a conditional copula model for the missingness mechanism.
result Provides a new method for estimating conditional survival function with MNAR censoring indicators.
Machine learning improves kidney transplant outcomes prediction.
problem Improving prediction of kidney transplant success.
method Random forest machine learning model trained on kidney donor risk index data.
result Random forest predicted 2,148 more successful transplants than the risk index.
Hidden Markov jump processes are an attractive approach for modeling clinical disease progression data because they are explainable and capable of handling both irregularly sampled and noisy data. Most applications in this context consider time-homogeneous models due to their relative computational simplicity. However,…
A fundamental question in data analysis, machine learning and signal processing is how to compare between data points. The choice of the distance metric is specifically challenging for high-dimensional data sets, where the problem of meaningfulness is more prominent (e.g. the Euclidean distance between images). In this…
Non-parametric estimators improve quickest changepoint detection under irregular sequence lengths.
problem Limited and irregular sequence lengths hinder application of ARL and ADD in QCD.
method Analogies with survival analysis to model detection probabilities under truncation.
result KM-ARL and KM-ADD non-parametric estimators are asymptotically unbiased.
An accurate model of a patient's individual survival distribution can help determine the appropriate treatment for terminal patients. Unfortunately, risk scores (e.g., from Cox Proportional Hazard models) do not provide survival probabilities, single-time probability models (e.g., the Gail model, predicting 5 year prob…
Develops algorithms to optimize machine replacement schedules using operational data.
problem Optimizing machine replacement intervals when the lifetime distribution is unknown.
method Formulates as a stochastic multi-armed bandit problem and proposes Hoeffding- and Bernstein-based algorithms.
result Achieves optimal or near-optimal replacement intervals with minimal regret.
Copula-based fusion improves breast cancer risk stratification.
problem Combining clinical and genomic risk scores using simple rules fails to capture their joint relationship.
method Used copulas to model the joint relationship between clinical and genomic risk scores.
result Copula-based fusion improves risk stratification, identifying subgroups with the worst prognosis.
Quantum neural networks improve causal inference in biomedical studies, especially for small samples.
problem Addressing selection bias in comparing surgical techniques using observational data.
method Developed QNN-based propensity score models focusing on four key covariates (Age, Sex, Stage, BMI). Employed a linear ZFeatureMap for data encoding, SummedPaulis for predictions, and CMA-ES for optimization. Integrated noise modeling to enhance predictive stability.
result QNNs, particularly with noise-aware strategies, outperformed classical models in small samples, achieving AUC up to 0.750 for n=100.
Study evaluates multi-omics data's role in predicting cancer survival.
problem Determining the usefulness of multi-omics data for predicting disease outcomes.
method 5-fold cross-validation with 12 prediction methods applied to 18 cancer datasets.
result Multi-omics data generally improves prediction performance, but not consistently.
Survival analysis of 832,941 Solana token launches shows a significant decline in graduation rate.
problem Analyzing the survival rate of Solana token launches and identifying factors affecting graduation.
method Survival analysis using Kaplan-Meier and Cox proportional-hazards models.
result The survival rate of Solana token launches has declined significantly, with a 3.18x decrease from previous rates.
Study predicts when ALS patients will lose speech, swallowing, etc. based on covariates.
problem Predicting when ALS patients will experience significant functional decline.
method Multi-event survival analysis, covariate-based models.
result Covariate-based models outperform Kaplan-Meier estimator in predicting time-to-event outcomes.