Bayesian nonparametric method estimates individualized treatment-response curves from observational data.
problem Estimating individualized treatment-response curves from observational time series data.
method Developed a Bayesian nonparametric method using the G-computation formula.
result BNP method provides more accurate estimates of treatment responses than alternative approaches.
New method estimates individual dose-response curves for any number of treatments.
problem Estimating individual dose-response curves for varied exposures.
method Neural network approach for learning counterfactual representations.
result Set a new state-of-the-art in estimating individual dose-response curves.
ContiVAE estimates individual dose-response curves from unobserved confounders using observational data.
problem Estimating causal effects of continuous treatments considering unobserved confounders.
method Variational auto-encoder with a Tilted Gaussian prior distribution modeling hidden confounders as latent variables.
result ContiVAE outperforms existing methods by up to 62% in predicting individual dose-response curves.
New method estimates treatment effects over time with unobserved confounders.
problem Estimating treatment effects from observational data with unobserved confounders.
method Sequential Deconfounder using Gaussian process latent variable model.
result Unbiased estimates of individualized treatment responses over time.
New method estimates treatment-response curves with covariate and timing measurement errors.
problem Estimating treatment impact on continuous temporal response with covariate measurement errors.
method Combines parametric response functions and sparse Gaussian process for baseline trend, considering both treatment covariates and timing errors.
result Significant improvements in estimation accuracy and prediction for diet impact on blood glucose measurements.
Proposes a deep learning framework for estimating counterfactual outcomes.
problem Challenges in estimating individual outcomes under different treatments.
method Deep variational Bayesian framework integrating factual and similar subjects' outcomes.
result Rigorously integrates individual features and similar subjects' responses for counterfactual outcomes.
A new algorithm learns optimal personalized treatment plans online with low regret.
problem Learning optimal dynamic treatment regimes in an online setting.
method Developed a novel algorithm balancing exploration and exploitation for rate-optimal regret.
result Guaranteed rate-optimal regret for linear transition and reward models.
Estimates individualized treatment effects using shared RBF-net neurons.
problem Identifying differential treatment effects based on covariates.
method Non-parametric radial basis function (RBF)-nets with shared hidden neurons in a Bayesian framework.
result Demonstrated through simulations and real data, the method identifies interesting treatment effects.
Bayesian model ranks treatments in multi-response experiments.
problem Identifying the best treatment among competing ideal properties.
method Bayesian approach with Markov Chain Monte Carlo algorithm.
result Reliable inference of treatment ranks in practice.
Proposes a method for generating prediction intervals in dose-response models using conformal prediction.
problem Uncertainty quantification in continuous treatments for personalized healthcare decisions.
method Causal dose-response problem framed as covariate shift, using weighted conformal prediction with propensity estimation and kernel functions.
result Demonstrates the significance of covariate shift assumptions for robust prediction intervals.
Paper models treatment effects by clustering patients with distinct survival characteristics.
problem Estimating treatment efficacy in clinical settings with censored outcomes.
method Latent variable approach to model heterogeneous treatment effects.
result The latent structure can mediate base survival rates and reveal actionable phenotypes.
Random forests improve individual treatment effect estimation in observational data.
problem Estimating individual treatment effects in observational data due to confounding and selection bias.
method Using random forests within the counterfactual framework to directly model the response.
result Accurate estimation of individual treatment effects possible even in complex settings.
Method estimates optimal treatment from crossover studies.
problem Estimating optimal treatment from crossover designs.
method Outcome weighted learning adapted to crossover designs.
result Improved performance compared to parallel study methods.
IntelligentPooling improves treatment decisions in mHealth.
problem Optimizing treatment decisions in mobile health with limited data and non-stationary responses.
method Generalized Thompson-Sampling bandit algorithms to IntelligentPooling, addressing differential response, limited data, and non-stationary responses.
result IntelligentPooling achieves 26% lower regret compared to state-of-the-art methods.
Estimating treatment effects in time series with hidden confounding.
problem Estimating treatment effects in time series with hidden confounding.
method A neural framework that learns individual-level counterfactuals and flexible matching procedures.
result Improves counterfactual estimation under latent bias.
Estimates individual treatment effects using gradient interpolation and kernel smoothing.
problem Estimating individualized continuous treatment effects in observational data.
method Augment training data with independently sampled treatments and inferred counterfactual outcomes using gradient interpolation and kernel smoothing.
result Our method outperforms state-of-the-art methods on counterfactual estimation error.
Optimal learning method for personalized treatment regimes.
problem Finding the best treatments for individual patients to maximize patient responses.
method Bayesian approach with contextual bandits and knowledge gradient policy.
result Significant improvement in treatment success rates through careful physician selection.
Reinforcement learning improves uplift modeling's accuracy.
problem Directly modeling the incremental impact of treatments on responses.
method Reformulated as a Markov Decision Process (MDP).
result Significant improvement over previous methods in both synthetic and real-world scenarios.
This work addresses causal inference challenges in networked interference and proposes GNN-based estimators for individual treatment effects.
problem Estimating individual treatment effects in randomized experiments with networked interference.
method Uses Graph Neural Networks (GNNs) to capture network dependencies and derive causal effect estimators.
result Provides policy regret bounds and heuristic error bounds for GNN-based causal estimators under network interference and treatment capacity constraints.
Study shows auditing fairness of personalized interventions is impossible due to unknown ground truths.
problem Auditing fairness of personalized interventions in social services, education, and healthcare.
method Point-identification of quantities under monotone treatment response assumption, providing sensitivity analysis for violations.
result Proves impossibility of auditing fairness using standard metrics and provides methods for auditing using partially-identified ROC and xROC curves.
Study optimal and equitable encouragement policies for treatment adherence.
problem Optimal treatment adherence policies in the presence of human non-adherence.
method Covariate-conditional no-direct-effect model of encouragement; tractable policy characterizations under constraints.
result Induced treatment take-up is the fairness target, not recommendation rates.
Proposes a novel method to cluster individuals based on treatment effects.
problem Identifying subpopulations with different treatment responses.
method Clusters individuals using a learned kernel derived from causal forests, revealing latent subgroup structures.
result Captures meaningful treatment effect heterogeneity through kernelized clustering.
EB-VAE combines tumor growth and dropout data for personalized treatment response modeling.
problem Challenges in integrating longitudinal tumor measurements, dropout information, and genetic covariates.
method Extended EB-VAE framework to jointly model longitudinal and time-to-event data, incorporating dropout hazard and genetic covariates.
result Hybrid decoder formulation yields consistent treatment-effect parameters and prior predictive performance comparable to neural decoder.
New method optimizes individualized decision rules for precision medicine.
problem Heterogeneous patient responses to treatments.
method Proposes a decision-rule based optimized covariates dependent equivalent (CDE) for individualized decision making.
result Numerical experiments show improved performance in estimating optimal IDRs.
CAST models time-varying treatment effects in cancer patients.
problem Estimating treatment effects at fixed time points limits understanding of dynamic changes over time.
method CAST combines parametric and non-parametric methods to model continuous time-varying treatment effects.
result CAST reveals how treatment effects rise, peak, and decline over the follow-up period.
Bayesian Causal Forest models estimate treatment effects with noncompliance.
problem Estimating treatment effects with noncompliance and varying compliance rates.
method Bayesian Causal Forest model for binary response variables.
result Flexibly estimate heterogeneous treatment effects among compliers.
Objectives: Electronic health records (EHRs) are only a first step in capturing and utilizing health-related data - the challenge is turning that data into useful information. Furthermore, EHRs are increasingly likely to include data relating to patient outcomes, functionality such as clinical decision support, and gen…
Personalized models explain TB treatment outcomes considering patient context.
problem Heterogeneity in TB treatment outcomes due to co-morbidities.
method Multi-task learning approach encoding patient context into personalized models.
result Identifies anemia, age of onset, and HIV as influential for treatment efficacy.
IPGP framework improves psychological assessment by integrating shared and unique traits.
problem Tackles the debate on shared vs unique personality traits across individuals.
method Uses Gaussian process coregionalization model for non-Gaussian ordinal data, with stochastic variational inference for scalability.
result Improves prediction and estimation of individualized factor structures compared to existing methods.
Study benchmarks contextual bandit algorithms for precision oncology using in vitro data.
problem Designing effective protocols for individual treatment assignment in precision oncology.
method Proposed a benchmark dataset of in vitro drug responses to evaluate contextual bandit algorithms.
result Bayesian bandit algorithms performed better than a rule-based baseline in minimizing regret.
PDX studies help personalize cancer treatment.
problem Precision medicine in cancer treatment.
method Machine learning methods for estimating optimal ITRs from PDX data.
result Superlearner approach combining multiple ITRs improves personalized treatment recommendations.
NCoRE learns counterfactual representations for combined treatments.
problem Estimating individual response to multiple simultaneous interventions.
method Neural conditional representation with modulators for cross-treatment interactions.
result NCoRE significantly outperforms existing methods in counterfactual treatment effect estimation.
Flexible modeling of continuous treatment-response curves for observational data.
problem Estimating treatment effects with varying continuous-time, continuous-valued interventions and irregularly measured outcomes.
method Representing treatment response curves with linear time-invariant dynamical systems and multiple-output Gaussian Processes.
result Significant gains in accuracy over state-of-the-art models on simulated and clinical datasets.
The paper studies how and when a treatment triggers different effects for individuals.
problem Estimating how treatment effects vary among individuals based on their characteristics.
method Tree-based learning method to find individual-level treatment triggers.
result The proposed method learns treatment triggers better than existing approaches.
Unified framework for response-adaptive targeting in multi-treatment experiments
problem Improving ethical and statistical efficiency in multi-treatment clinical trials
method Response-adaptive targeting strategies
result Unified framework for α-Rebalancing Targeting Strategies (αRTS) Study predicts internet-based treatment effects for GPPPD based on dyadic coping.
problem Identifying which patients will benefit most from internet-based GPPPD treatment.
method Developed a multivariable decision tree model using recursive partitioning.
result Predicts large effects for high dyadic coping patients, small effects for low dyadic coping patients.
Three approaches learn personalized treatment policies for UTI patients.
problem Learning optimal treatment policies in multiobjective settings with fully observed outcomes.
method Indirect and direct approaches using predictive models and without intermediate models.
result All approaches outperform clinicians in achieving better performance on all outcomes and trade-offs.
Classifies treatment responders using monotonic causal effects.
problem Predicting treatment response based on features and past examples.
method Developed discriminative and generative algorithms leveraging monotonicity.
result New algorithms outperform standard benchmarks in responder classification.
Estimates personalized treatment response curves using covariates.
problem Flexible estimation of personalized treatment response curves.
method Sieve based nonparametric estimator of smoothed regimen-response curve function.
result Asymptotic linearity and undersmoothing criteria for efficient estimation.
Heteroskedasticity biases uplift model rankings, leading to inefficient treatment allocation.
problem Bias in uplift model rankings due to heteroskedasticity.
method Theoretical analysis and simulation on real-world data.
result Heteroskedasticity can cause individuals with high treatment effects to be ranked at the bottom, leading to inefficient treatment allocation.
New methods needed to estimate individual treatment effects.
problem Estimating treatment effects on individual level.
method Machine learning for subgroup discovery under treatment effect.
result Efficient methods are needed for estimating individual treatment effects.
Large dataset released for ITE and UM research.
problem Estimating causal impact of actions in various sectors.
method Release of a large dataset, formalization of UM, synthetic response surfaces, heterogeneous treatment assignment.
result Validation of ITE prediction and UM methods with high statistical significance.
The paper compares methods for estimating individual treatment effects.
problem Estimating the optimal treatment effect for each individual.
method Comparison of machine learning methods for individual treatment effect estimation.
result Combination of Logistic Regression and Difference Score method, as well as Uplift Random Forest method, provides the best prediction accuracy.
Proposes a new model for estimating individual treatment effects.
problem Estimating individual treatment effects from observational data is challenging.
method Integrates diffusion modeling and conformal inference with propensity score and covariate approximation.
result Establishes rigorous theoretical guarantees and demonstrates competitive performance.
The paper clarifies the distinction between CATE and ITE under ignorability assumptions.
problem Confusion between CATE and ITE hinders personalized effect estimation.
method Clarifies the distinction between CATE and ITE under ignorability assumptions.
result CATE and ITE are not necessarily the same under ignorability assumptions.
Develops methods for near-optimal personalized treatment recommendations.
problem Assigning optimal treatments to patients based on individual characteristics.
method Outcome weighted learning framework to estimate near-optimal alternative individualized treatment recommendations (A-ITR).
result Consistency of proposed methods and upper bound for risk between optimal and estimated recommendations.
Estimates CATE under hidden confounding, accounting for bias and ignorance.
problem Learning CATE from high-dimensional data with unobserved confounders introduces bias and ignorance.
method Parametric interval estimator that accounts for hidden confounding and underrepresented samples.
result Estimator converges to tight bounds on CATE when there may be unobserved confounding.
GraphITE estimates individual effects of graph-structured treatments.
problem Estimating individual effects of complex treatment structures.
method Graph neural networks and Hilbert-Schmidt Independence Criterion regularization.
result GraphITE outperforms baselines in estimating treatment effects for large numbers of treatments.