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6 results for IBD

Study uses machine learning to identify IBD biomarkers from gut microbiota.

problem Identifying biomarkers for Inflammatory Bowel Disease (IBD) from gut microbiota.
method Ensemble feature selection methods (CMIM, FCBF, mRMR, XGBoost) applied to IBD-associated metagenomics dataset.
result XGBoost minimizes microbiota used for IBD diagnosis, improving classification accuracy.

Pipeline integrates cross-sectional and longitudinal multi-omics data for IBD research.

problem Integrating diverse data types from the same individuals for disease understanding.
method Statistical and deep learning methods for variable selection, feature extraction, and joint integration.
result Identified microbial pathways, metabolites, and genes discriminating IBD status.

Unified method for discovering biclusters and triclusters in longitudinal data.

problem High-dimensional, sparsely sampled, irregularly observed longitudinal data.
method Tri-SfSVD, a unified sparse functional Singular Value Decomposition framework.
result Identified localized structures at the subject, subject-feature, and subject-feature-time levels.

Donor-aware scRNA-seq benchmarks improve classification accuracy in inflammatory bowel disease.

problem Influenza disease classification from scRNA-seq data is prone to donor-level confounding.
method Developed and evaluated three feature representations across two IBD cohorts.
result Compartment-stratified CLR composition and GatedStructuralCFN embeddings outperform linear models in classification accuracy.

Crohn's disease, one of two inflammatory bowel diseases (IBD), affects 200,000 people in the UK alone, or roughly one in every 500. We explore the feasibility of deep learning algorithms for identification of terminal ileal Crohn's disease in Magnetic Resonance Enterography images on a small dataset. We show that they …

2019-08-31abs ↗pdf ↗