Survey on securing ML for healthcare, addressing privacy and robustness issues.
problem Security and robustness challenges in healthcare ML/DL applications.
method Overview of security and privacy methods for ML in healthcare.
result Discussion of current research challenges and future directions.
Unified framework for imputation and prediction in healthcare time series.
problem Time misalignment and data sparsity in healthcare time series.
method MAGIC (Multi-tAsk Gaussian Process for Imputation and Classification) using hierarchical multi-task Gaussian process and functional logistic regression.
result Superior predictive accuracy compared to existing methods in two healthcare applications.
This tutorial evaluates machine learning for healthcare applications.
problem Unrealistic expectations in healthcare AI development.
method Practical guidance on performance evaluation criteria and common mistakes.
result Better understanding and avoidance of common traps in AI healthcare.
Big data analytics improves healthcare through early detection and quality life.
problem Limited access to healthcare data hinders evidence-based decision-making.
method Analysis of healthcare data using various tools and techniques.
result Big data analytics enhances healthcare quality and patient outcomes.
A broad spectrum of data from different modalities are generated in the healthcare domain every day, including scalar data (e.g., clinical measures collected at hospitals), tensor data (e.g., neuroimages analyzed by research institutes), graph data (e.g., brain connectivity networks), and sequence data (e.g., digital f…
Enhances understanding of patient healthcare journeys using self-attention.
problem Capturing hidden dependencies in multi-level patient journey data.
method Proposes a multi-level self-attention network (MusaNet) for encoding patient journeys.
result MusaNet produces higher-quality representations than state-of-the-art methods.
Proposes a method to improve rare event prediction in healthcare.
problem Rare event classification in healthcare with low prevalence labels.
method Variational disentanglement approach to semi-parametric learning.
result Outperforms existing alternatives in mortality prediction on COVID-19 cohort.
A recommendation framework helps users choose healthcare interventions.
problem Choice overload in online healthcare communities.
method Multi-Armed Bandit (MAB) approach with innovative model components.
result Our recommendation design outperforms state-of-the-art systems.
TRACER improves interpretability in high stakes analytics.
problem Interpreting complex models in high stakes applications.
method TRACER framework with TITV model for healthcare analytics.
result TRACER facilitates both accurate and interpretable analytics.
Paper addresses data heterogeneity in federated learning for CoxPH models in healthcare.
problem Data heterogeneity in federated learning of CoxPH models for healthcare.
method Feature-based clustering and event-based reporting strategy.
result Enhanced model accuracy and performance in federated survival analysis.
Deep learning analyzes healthcare provider actions and patient outcomes.
problem Understanding provider behavior in non-randomized healthcare settings.
method Deep causal behavioral policy learning (DC-BPL) using transformer architecture.
result Optimal provider policies identified for specific patient types.
New method sparsifies hybrid neural ODEs for better performance and stability.
problem Excessive latent states and interactions from mechanistic models lead to training inefficiency and over-fitting.
method Automatic state selection and structure optimization combining domain-informed graph modifications with data-driven regularization.
result Improved predictive performance and robustness with desired sparsity.
The Temporal Group LASSO is an example of a multi-task, regularized regression approach for the prediction of response variables that vary over time. The aim of this work is to introduce the reader to the concepts behind the Temporal Group LASSO and its related methods, as well as to the type of potential applications …
This guide introduces machine learning for medical data analysis.
problem Handling large, complex datasets in healthcare.
method Explains common machine learning algorithms and tasks.
result Illustrates machine learning applications in healthcare.
Representation learning methods that transform encoded data (e.g., diagnosis and drug codes) into continuous vector spaces (i.e., vector embeddings) are critical for the application of deep learning in healthcare. Initial work in this area explored the use of variants of the word2vec algorithm to learn embeddings for m…
Super learner with Huber loss improves cost prediction and causal effect estimation in healthcare expenditure data.
problem Challenges in modeling healthcare expenditure distributions with standard super learning methods.
method Proposes a super learner using Huber loss, a robust loss function that down-weights outliers.
result Demonstrates appreciable finite-sample gains in cost prediction and causal effect estimation.
Probabilistic ML improves healthcare data analysis.
problem Insufficient understanding and incomplete data in healthcare.
method Examination of probabilistic machine learning models for healthcare challenges.
result Probabilistic models enhance healthcare data analysis and model building.
A statistical description and model of individual healthcare expenditures in the US has been developed for measuring value in healthcare. We find evidence that healthcare expenditures are quantifiable as an infusion-diffusion process, which can be thought of intuitively as a steady change in the intensity of treatment …
Unified RL survey for healthcare AI interventions.
problem Limited real-life application of RL in healthcare.
method Unified technical survey and case studies.
result Bridge between dynamic treatment regimes and mobile health.
A new method uses Hamiltonian Monte Carlo for imputation and augmentation of healthcare data.
problem Missing values in clinical studies lead to biased results and loss of statistical power.
method Folded Hamiltonian Monte Carlo (F-HMC) with Bayesian inference to handle high-dimensional, small sample size datasets.
result The method enriches the quality of data in precision, accuracy, recall, F1 score, and propensity metric.
FOCUS addresses label quality disparity in FL for healthcare applications.
problem Label quality disparity in federated learning for healthcare applications.
method FOCUS maintains a small set of benchmark samples and computes the mutual cross-entropy between local and benchmark datasets to quantify label credibility. It then adjusts client weights based on credibility values.
result FOCUS effectively reduces the impact of noisy labels from clients, improving model performance.
MCU-Net combines U-Net and Monte Carlo Dropout for uncertainty in medical image segmentation.
problem Lack of uncertainty representation in deep learning methods for patient-centered healthcare decisions.
method MCU-Net framework using U-Net and Monte Carlo Dropout with four uncertainty metrics.
result MCU-Net maximizes automated performance and refers truly uncertain cases.
Develops privacy-preserving methods for equivalence testing in healthcare.
problem Protecting patient data in healthcare studies.
method Differential privacy techniques for simulation-based calibration.
result Maintains type-I error control and comparable power to non-private methods.
The study diagnoses fairness issues in healthcare models under distribution shifts.
problem Understanding and diagnosing fairness changes in machine learning models under distribution shifts in healthcare.
method Causal framing and conditional independence tests to characterize distribution shifts.
result Knowledge of distribution shifts helps diagnose fairness transfer failures, including complex cases.
Study user engagement in mobile health apps for health workers in resource-poor settings.
problem Detect churn and tailor content for health workers in mobile health apps.
method Probabilistic and survival analysis of behavioral logs.
result Personalized measures of meaningful engagement can enhance health outcomes.
One of the main issues affecting the Italian NHS is the healthcare deficit: according to current agreements between the Italian State and its Regions, public funding of regional NHS is now limited to the amount of regional deficit and is subject to previous assessment of strict adherence to constraint on regional healt…
This paper solves the problem of optimal dynamic consumption, investment, and healthcare spending with isoelastic utility, when natural mortality grows exponentially to reflect Gompertz' law and investment opportunities are constant. Healthcare slows the natural growth of mortality, indirectly increasing utility from c…
Improves off-policy evaluation with imperfect annotations.
problem Limited dataset coverage for evaluating new policies.
method Doubly robust estimators combining IS and DM, incorporating counterfactual annotations.
result Using annotations within the DM component yields the most desirable theoretical results.
GPT-4 assesses its confidence in answering USMLE questions with and without feedback.
problem Understanding AI's performance in healthcare applications, especially in sensitive areas like medical education.
method Used a prompting technique to evaluate GPT-4's confidence scores before and after answering USMLE questions, categorized into with and without feedback.
result Feedback influences relative confidence but doesn't consistently increase or decrease it.
auton-survival simplifies survival analysis for healthcare data.
problem Handling censored time-to-event data in healthcare.
method Open-source package for survival regression, adjustment, counterfactual estimation, phenotyping, and treatment effects.
result Demonstrates auton-survival's ability to support complex health and epidemiological questions.
Study optimal healthcare spending under Epstein-Zin preferences for longevity.
problem Optimizing healthcare spending to extend longevity under Epstein-Zin preferences.
method Formulated Epstein-Zin utilities over a controllable random horizon using backward stochastic differential equations and HJB equations.
result Calibrated model accurately reflects actual mortality data and compares healthcare efficacy between countries.
Study improves conformal prediction for EEG classification in healthcare, enhancing coverage.
problem Uncertainty quantification in clinical predictions, especially in distribution-shifted settings.
method Personalized calibration strategies to improve coverage of prediction sets.
result Coverage improved by over 20 percentage points with comparable prediction set sizes.
The rapid growth of Electronic Health Records (EHRs), as well as the accompanied opportunities in Data-Driven Healthcare (DDH), has been attracting widespread interests and attentions. Recent progress in the design and applications of deep learning methods has shown promising results and is forcing massive changes in h…
Interpretability of ML models improves healthcare decisions.
problem Ensuring machine learning models are understandable for healthcare users.
method Classifying interpretability into local and global approaches, and model-specific vs. model-agnostic methods.
result Examples of practical interpretability in healthcare, including prediction and treatment optimization.
Deep learning models (aka Deep Neural Networks) have revolutionized many fields including computer vision, natural language processing, speech recognition, and is being increasingly used in clinical healthcare applications. However, few works exist which have benchmarked the performance of the deep learning models with…
Paper analyzes uncertainty metrics in ensemble learning for healthcare AI.
problem Selecting appropriate uncertainty metrics for ensemble learners in healthcare AI.
method Rigorous analysis of two uncertainty metrics: ensemble mean and variance.
result Ensemble mean is preferable to ensemble variance for decision making in healthcare AI.
As much as data science is playing a pivotal role everywhere, healthcare also finds it prominent application. Breast Cancer is the top rated type of cancer amongst women; which took away 627,000 lives alone. This high mortality rate due to breast cancer does need attention, for early detection so that prevention can be…
Paper improves MRI reconstruction by separating target labels and prediction error.
problem Improving MRI reconstruction accuracy by estimating prediction error.
method Proposes a novel method to estimate target labels and prediction error separately.
result Significantly better MRI reconstruction results achieved compared to state-of-the-art methods.
Distributed representations have been used to support downstream tasks in healthcare recently. Healthcare data (e.g., electronic health records) contain multiple modalities of data from heterogeneous sources that can provide complementary information, alongside an added dimension to learning personalized patient repres…
A new method synthesizes expressions from characteristics using GAN for healthcare.
problem Synthesizing expressions from given characteristics in high-dimensional space.
method Generative Adversarial Network (GAN) based selective ensemble learning.
result The proposed SE-CTES method effectively handles deterministic and stochastic patterns.
LMM predicts healthcare costs and risks with improved accuracy.
problem Wasteful healthcare spending and inefficiencies in risk prediction.
method Generative pre-trained transformer trained on patient event sequences.
result Improves cost prediction by 14.1% and chronic conditions prediction by 1.9%.
Study improves healthcare time series imputation by considering structured missingness.
problem Structured missingness in clinical data impacts time series imputation models.
method Analysis of different masking strategies on imputation methods using PhysioNet Challenge 2012 dataset.
result Masking choices significantly affect imputation accuracy and clinical prediction.
Batteryless or so called passive wearables are providing new and innovative methods for human activity recognition (HAR), especially in healthcare applications for older people. Passive sensors are low cost, lightweight, unobtrusive and desirably disposable; attractive attributes for healthcare applications in hospital…
Methodology creates holdout and test/train sets for ML studies, preserving data for future research.
problem Preserving data for future research studies that are analysis-naive.
method Modification of k-fold cross-validation, randomization, and three-way split (holdout, test, training).
result Efficiently creates holdout and test/train sets without forcing.
While artificial intelligence (AI) and other automation technologies might lead to enormous progress in healthcare, they may also have undesired consequences for people working in the field. In this interdisciplinary study, we capture empirical evidence of not only what healthcare work could be automated, but also what…
CARRNN tackles deep learning for sporadic data, improving prediction errors in healthcare.
problem Challenges in learning temporal patterns from sporadic multivariate longitudinal data.
method Developed a novel deep learning architecture combining RNN and CAR models, using a generalized discrete-time autoregressive model.
result CARRNN achieves the lowest prediction errors in multivariate time-series regression tasks.
In application domains such as healthcare, we want accurate predictive models that are also causally interpretable. In pursuit of such models, we propose a causal regularizer to steer predictive models towards causally-interpretable solutions and theoretically study its properties. In a large-scale analysis of Electron…
Deep learning models exhibit state-of-the-art performance for many predictive healthcare tasks using electronic health records (EHR) data, but these models typically require training data volume that exceeds the capacity of most healthcare systems. External resources such as medical ontologies are used to bridge the da…