Paper proposes a method to model health outcomes using varying-coefficients and KNN-based LASSO.
problem Modeling health outcomes like BMI and cholesterol levels with varying age effects.
method Varying-coefficients regional quantile regression via KNN fused LASSO, with ADMM algorithm.
result Efficacy in capturing complex age-dependent associations between health outcomes and risk factors.
Infinite hierarchical contrastive clustering identifies personal environments linked to health outcomes.
problem Identifying meaningful relationships between environmental features and health outcomes on an individual level.
method Contrastive clustering framework with stick-breaking prior and participant-specific prediction loss.
result Model effectively identifies distinct personal environments and groups them into meaningful types linked to health outcomes.
Deep learning using neural networks has provided advances in image style transfer, merging the content of one image (e.g., a photo) with the style of another (e.g., a painting). Our research shows this concept can be extended to analyse the design of streetscapes in relation to health and wellbeing outcomes. An Austral…
Patient journeys are compared to find clusters of similar disease trajectories.
problem Discovering shared health outcomes among patient journeys.
method Comparing longitudinal health data to identify clusters of similar patient trajectories.
result Clusters of patient journeys with similar health outcomes can be identified.
MLHO predicts COVID-19 adverse outcomes using past medical records.
problem Predicting adverse outcomes after COVID-19 infection.
method Iterative feature and algorithm selection, sequential representation mining.
result Mean AUC ROC of 0.91 for mortality prediction.
Two new estimators reduce costs and improve accuracy for EHR outcome prediction.
problem Sparse estimate distributions, high computational cost, and high sampling variance in EHR outcome prediction.
method Proposed SCOPE and REACH estimators that leverage next-token probability distributions.
result SCOPE and REACH match Monte Carlo accuracy with token reductions of 2.5-3.4 times and variance guarantees.
Efficient RL method uses SSL for small labeled data in health outcomes.
problem Lack of precise health outcome data for reinforcement learning.
method Semi-supervised learning approach for Q-learning and value estimation.
result Method efficiently estimates Q-function and value function, robust to mis-specification.
Develops a personalized reinforcement learning algorithm for dyadic health interventions.
problem Personalizing health interventions for dyadic relationships in mobile health.
method Dyadic Reinforcement Learning (dyadic RL), a Bayesian and hierarchical online algorithm.
result Established a regret bound and demonstrated empirical performance through simulations and real data.
Study assesses weakly-supervised methods for rare outcomes in medical records.
problem Identifying patients with specific medical conditions using electronic health records.
method Compared three methods (PheNorm, MAP, and sureLDA) in simulations with varying outcomes and silver labels.
result No single method consistently outperformed others, but sureLDA often did well.
New models automate support group formation in online health communities.
problem Challenges in traditional support group formation methods for scalability, static categorization, and insufficient personalization.
method Two novel machine learning models: gDMR and gSTM, integrating user content, demographics, and network data.
result Models outperform baselines in predictive accuracy, semantic coherence, and internal group consistency.
Paper develops methods for evaluating mHealth interventions using historical data.
problem Evaluating the long-term effectiveness of mHealth interventions designed for near-term outcomes.
method Develops off-policy estimation techniques to infer long-term average outcomes from historical data.
result Provides estimators and confidence intervals for evaluating mHealth policies.
mcanalysis quantifies menstrual cycle effects in health data.
problem Lack of standardised statistical methods for menstrual cycle research.
method Fourier-basis generalised additive model (GAM) pipeline.
result Nine out of 15 health outcomes showed significant association with menstrual cycle.
New method identifies proxies for causal effects on multiple outcomes.
problem Estimating causal effects in scenarios with multiple outcomes and treatments.
method Causal discovery method leveraging multiple outcomes as proxies for each treatment effect.
result Parallel studies of multiple outcomes can assist in causal identification.
Study optimizes health incentives to balance efficiency and fairness.
problem Designing health incentives to balance efficiency and fairness.
method Inverse behavioral optimization framework integrating QALY-based incentives and adaptive learning.
result Modern health systems operate near an efficiency-saturated frontier, with small fairness adjustments yielding diminishing returns.
Satellite images predict U.S. county mortality rates.
problem Predicting mortality rates in U.S. counties using satellite imagery.
method Convolutional neural network trained on crude mortality rates, learned features interpreted using Shapley Additive Feature Explanations.
result Predicted mortality from satellite images correlated strongly with true mortality rates (Pearson r=0.72).
Electronic health records are an increasingly important resource for understanding the interactions between patient health, environment, and clinical decisions. In this paper we report an empirical study of predictive modeling of several patient outcomes using three state-of-the-art machine learning methods. Our primar…
Personalized predictive medicine necessitates the modeling of patient illness and care processes, which inherently have long-term temporal dependencies. Healthcare observations, recorded in electronic medical records, are episodic and irregular in time. We introduce DeepCare, an end-to-end deep dynamic neural network t…
Clinical outcome prediction based on the Electronic Health Record (EHR) plays a crucial role in improving the quality of healthcare. Conventional deep sequential models fail to capture the rich temporal patterns encoded in the longand irregular clinical event sequences. We make the observation that clinical events at a…
New method improves mHealth user engagement using Thompson sampling for count data.
problem Optimizing mHealth interventions for distal outcomes through proximal context.
method Combines count data models with Thompson sampling for contextual bandits.
result Improves user engagement in mHealth trials compared to existing methods.
Objectives: Electronic health records (EHRs) are only a first step in capturing and utilizing health-related data - the challenge is turning that data into useful information. Furthermore, EHRs are increasingly likely to include data relating to patient outcomes, functionality such as clinical decision support, and gen…
New AI model optimizes personalized care for elderly residents.
problem Limited care workforce impacts health outcomes and quality of life.
method Bandit algorithms for personalized care planning.
result Improves care quality and health outcomes through personalized care planning.
Study user engagement in mobile health apps for health workers in resource-poor settings.
problem Detect churn and tailor content for health workers in mobile health apps.
method Probabilistic and survival analysis of behavioral logs.
result Personalized measures of meaningful engagement can enhance health outcomes.
LHIEM model predicts health, income, and employment over years.
problem Lack of path dependency in health policy simulations.
method Discrete-time microsimulation with Markov chain modules.
result Validates health care financing proposal through detailed modeling.
The distribution of health care payments to insurance plans has substantial consequences for social policy. Risk adjustment formulas predict spending in health insurance markets in order to provide fair benefits and health care coverage for all enrollees, regardless of their health status. Unfortunately, current risk a…
New method uses surrogate outcomes and single-record data to improve suicide risk modeling.
problem Lack of historical information in single-record patients hinders modeling rare medical events.
method Hybrid framework combining supervised and unsupervised learning to integrate concurrent and single-record data.
result Single-record data and concurrent diagnoses provide valuable information for improving suicide risk modeling.
Deep learning predicts drug prescriptions across global health records.
problem Predicting drug prescriptions in chronic disease patients.
method Adaptive cross-global attention graph kernel network with support vector machine.
result Model outperforms current methods in accuracy and interpretability.
We study how language on social media is linked to diseases such as atherosclerotic heart disease (AHD), diabetes and various types of cancer. Our proposed model leverages state-of-the-art sentence embeddings, followed by a regression model and clustering, without the need of additional labelled data. It allows to pred…
Study uses machine learning to predict future health from various health data types.
problem Predicting future health using diverse health data types.
method Applied machine learning (neural networks and XGBoost) to longitudinal data from 6830 individuals.
result Health-related measures were the strongest predictors of future health status, while genetic data performed poorly.
With the increased availability of large databases of electronic health records (EHRs) comes the chance of enhancing health risks screening. Most post-marketing detections of adverse drug reaction (ADR) rely on physicians' spontaneous reports, leading to under reporting. To take up this challenge, we develop a scalable…
The wide implementation of electronic health record (EHR) systems facilitates the collection of large-scale health data from real clinical settings. Despite the significant increase in adoption of EHR systems, this data remains largely unexplored, but presents a rich data source for knowledge discovery from patient hea…
Stable health predictions need deconfounding test set features.
problem Stability of predictions in health machine learning is compromised by selection biases.
method Deconfounding the test set features improves prediction stability across different environments.
result Improved stability achieved by deconfounding test set features.
Predict human lives using sequences of life events.
problem Predicting human life outcomes based on detailed event sequences.
method Adapting natural language processing techniques to analyze life events.
result Models predict diverse outcomes with high accuracy, outperforming state-of-the-art models.
CovidCare uses EMR data to predict patient outcomes in emerging epidemics.
problem Intelligent prognosis for patients with emerging infectious diseases during rapid epidemics.
method Transfer learning and knowledge distillation from existing EMR data.
result CovidCare outperforms baseline methods in predicting patient length of stay.
Method fuses low and high-resolution data for better health estimates.
problem Improving high-resolution health estimates from mixed data sources.
method Fusion of unbiased low-resolution and potentially biased high-resolution data, learning a distribution consistent with sampling bias.
result Significant reduction in bias in high-resolution estimates.
The opioid epidemic in the United States claims over 40,000 lives per year, and it is estimated that well over two million Americans have an opioid use disorder. Over-prescription and misuse of prescription opioids play an important role in the epidemic. Individuals who are prescribed opioids, and who are diagnosed wit…
Causal ML predicts treatment outcomes, aiding personalized medicine.
problem Predicting individualized treatment effects for personalized medicine.
method Flexible, data-driven methods using causal inference with clinical trial and real-world data.
result Causal ML allows for estimating individualized treatment effects.
New method combines multiple data sources for optimal decision-making with limited outcomes.
problem Optimal decision-making with limited outcome data from multiple heterogeneous sources.
method Calibrated optimal decision-making method leveraging common intermediate outcomes.
result Proposed estimator of conditional mean outcome is asymptotically normal and more efficient.
Predicting an individual's risk of experiencing a future clinical outcome is a statistical task with important consequences for both practicing clinicians and public health experts. Modern observational databases such as electronic health records (EHRs) provide an alternative to the longitudinal cohort studies traditio…
Study tackles variable selection with missing covariates and outcomes using machine learning and imputation.
problem Missing data in both covariates and outcomes complicates variable selection in health studies.
method Exploits machine learning flexibility and bootstrap imputation for variable selection, comparing multiple methods.
result XGBoost and BART perform best in variable selection with bootstrap imputation, achieving high F1 scores and low Type I errors. Enhances patient failure prediction using dynamic survival models.
problem Lack of precise individual level prediction in conventional models.
method Developed counterfactual dynamic survival model (CDSM).
result Inflection point of estimated survival curves predicts patient failure time.
CNN improves causal inference by controlling time-structured covariates.
problem Estimating the effect of early retirement on health outcomes while controlling for time-structured covariates.
method Used CNN to fit nuisance models explaining treatment and outcome, combining them into an augmented inverse probability weighting estimator.
result Uniformly valid inference achieved through CNN, providing rates of convergence and uniformly valid inference guarantees.
The health outcomes of high-need patients can be substantially influenced by the degree of patient engagement in their own care. The role of care managers includes that of enrolling patients into care programs and keeping them sufficiently engaged in the program, so that patients can attain various goals. The attainmen…
Imaging fluorescent disease biomarkers in tissues and skin is a non-invasive method to screen for health conditions. We report an automated process that combines intraoral fluorescent porphyrin biomarker imaging, clinical examinations and machine learning for correlation of systemic health conditions with periodontal d…
App enhances midwives' skills in low-income countries.
problem Low-income countries have high maternal and child mortality rates.
method Deep learning models predict midwives' interest in learning materials.
result Deep learning models accurately predict midwives' interest in learning materials.
A new method generates counterfactual treatment outcomes for time-varying treatments.
problem Estimating counterfactual outcomes for time-varying treatments with high-dimensional outcomes.
method Conditional generative framework with inverse probability re-weighting.
result Our method outperforms state-of-the-art baselines in generating high-quality counterfactual samples.
Databases of electronic health records (EHRs) are increasingly used to inform clinical decisions. Machine learning methods can find patterns in EHRs that are predictive of future adverse outcomes. However, statistical models may be built upon patterns of health-seeking behavior that vary across patient subpopulations, …
Diabetes is a major public health problem in the United States, affecting roughly 30 million people. Diabetes complications, along with the mental health comorbidities that often co-occur with them, are major drivers of high healthcare costs, poor outcomes, and reduced treatment adherence in diabetes. Here, we evaluate…
Language models improve clinical prediction models using EHR data.
problem Limited patient data for training clinical prediction models.
method Using patient representation schemes from natural language processing.
result 3.5% mean improvement in AUROC on five prediction tasks.