Simulation-based inference aids in predicting disease dynamics for health policy.
problem Predicting disease dynamics to inform public health interventions.
method Simulation-based inference using machine learning.
result Potential for efficient interpretable Bayesian inference in epidemiological models.
New algorithm forecasts health indicators for better equipment lifespan prediction.
problem Improving equipment lifespan prediction through health indicator forecasting.
method Generative + scenario matching approach using Gaussian Process.
result Superior performance compared to existing methods.
SaML guides ML models to avoid survey biases.
problem ML models trained on survey data often ignore survey design metadata.
method Nine-step guideline for incorporating survey design metadata in ML lifecycle.
result SaML provides valid population inference from survey data.
EHR-MPC optimizes sepsis treatment using digital twins and inference-time control.
problem Optimal sepsis treatment policies are contested and difficult to adapt during inference.
method EHR-MPC decouples learning patient dynamics from treatment optimization, enabling inference-time control over learned digital twins.
result EHR-MPC achieves comparable off-policy performance and improved simulation performance compared to RL baselines.
Bayesian method for imputing actigraph data from mobile devices.
problem Imputing missing actigraph data from mobile devices.
method Bayesian inference and hierarchical dynamic linear model.
result Statistical learning of time-varying impact of explanatory variables on acceleration.
Online health communities such as the online breast cancer forum enable patients (i.e., users) to interact and help each other within various subforums, which are subsections of the main forum devoted to specific health topics. The changing nature of the users' activities in different subforums can be strong indicators…
Federated learning for Bayesian clustering of large datasets.
problem Bayesian model-based clustering of large-scale binary and categorical data.
method Federated variational inference with local merge and delete moves in parallel batches, followed by global merge moves.
result Empirical validation shows superior performance compared to existing algorithms.
Topic modeling enables exploration and compact representation of a corpus. The CaringBridge (CB) dataset is a massive collection of journals written by patients and caregivers during a health crisis. Topic modeling on the CB dataset, however, is challenging due to the asynchronous nature of multiple authors writing abo…
Applying machine learning in the health care domain has shown promising results in recent years. Interpretable outputs from learning algorithms are desirable for decision making by health care personnel. In this work, we explore the possibility of utilizing causal relationships to refine diagnostic prediction. We focus…
The study corrects measurement error in evaluating health effects of multiple pollutants.
problem Bias in estimating health effects of air pollution constituents due to mismeasurement.
method Used a linear regression calibration model and extended DML approach to correct for measurement error.
result Identified two PM2.5 constituents (Br and Mn) that show a negative causal effect on cognitive function after correction.
Bayesian model identifies health disparities in disease progression.
problem Health disparities bias disease progression models.
method Interpretable Bayesian model accounting for three disparities.
result Model identifies and corrects for health disparities.
Semiparametric STAR model improves mental health data analysis.
problem Overdispersed, zero-inflated, bounded count data in self-reported mental health surveys.
method STAR transformation and rounding of latent Gaussian model, nonparametric transformation estimation, EM algorithm for maximum likelihood.
result Substantial improvements in goodness-of-fit compared to existing models.
Bayesian hypergraph inference models disease pathways from EHR data.
problem Modeling rare diseases influenced by shared risk factors.
method Bayesian hypergraph inference framework reframing multi-disease modeling.
result Interpretable disease pathways and well-calibrated uncertainty quantification.
Proposes statistical inference for dependency knowledge graphs from EHR data.
problem Statistical uncertainty in linking entities in EHR data.
method Dynamic log-linear topic model with singular value decomposition.
result Established asymptotic normality for sparse graph edge recovery.
Study uses machine learning to predict stroke risk in China with improved accuracy.
problem Predicting stroke risk in China using machine learning.
method Combines VAR and GNN for causal inference, compares multiple classification algorithms, uses SMOTE undersampling.
result Gradient Boosting model shows highest performance and stability in predicting stroke risk.
Privacy-preserving synthetic data from EHRs for learning and inference.
problem Sharing sensitive EHR data while maintaining patient privacy.
method Differentially private normalizing flows for density estimation and variational inference.
result Privacy-preserving synthetic data can yield good utility at a reasonable privacy cost.
Chagas disease is a neglected disease, and information about its geographical spread is very scarse. We analyze here mobility and calling patterns in order to identify potential risk zones for the disease, by using public health information and mobile phone records. Geolocalized call records are rich in social and mobi…
Bayesian mixture models inference in federated learning
problem Inference of Bayesian mixture models in federated learning
method Consensus Monte Carlo approach
result Recovery of small clusters with greater accuracy than standard MCMC
Extracting common narratives from multi-author dynamic text corpora requires complex models, such as the Dynamic Author Persona (DAP) topic model. However, such models are complex and can struggle to scale to large corpora, often because of challenging non-conjugate terms. To overcome such challenges, in this paper we …
Recently it's been shown that neural networks can use images of human faces to accurately predict Body Mass Index (BMI), a widely used health indicator. In this paper we demonstrate that a neural network performing BMI inference is indeed vulnerable to test-time adversarial attacks. This extends test-time adversarial a…
The paper reviews methods for estimating individual treatment effects using non-parametric regression models.
problem Estimating heterogeneous treatment effects in observational data.
method Non-parametric regression models to estimate individual treatment effects.
result A review and development of existing state-of-the-art frameworks for individual treatment effects estimation.
CNN improves causal inference by controlling time-structured covariates.
problem Estimating the effect of early retirement on health outcomes while controlling for time-structured covariates.
method Used CNN to fit nuisance models explaining treatment and outcome, combining them into an augmented inverse probability weighting estimator.
result Uniformly valid inference achieved through CNN, providing rates of convergence and uniformly valid inference guarantees.
Neural EKF improves structural dynamics prediction.
problem Accurately predicting structural response for health monitoring.
method Neural Extended Kalman Filter (Neural EKF) for learning dynamics.
result Significant predictive capabilities demonstrated on simulated and real-world data.
Method constructs prediction intervals for time-varying individual treatment effects.
problem Accurately quantify uncertainty of individual treatment effects across multiple decision points.
method Conformal inference techniques for time-varying ITEs with weaker assumptions.
result Guaranteed lower bound for coverage dependent on data non-exchangeability.
Study decomposes racial healthcare disparities via shifts in mediator distributions.
problem Racial disparities in healthcare expenditures and their underlying drivers.
method Framework decomposing disparities into mediator distribution shifts and residual components, using MEPS data.
result Substantial disparities persist even when mediators are equalized, suggesting unmeasured or structural factors.
Personalized predictive medicine necessitates the modeling of patient illness and care processes, which inherently have long-term temporal dependencies. Healthcare observations, recorded in electronic medical records, are episodic and irregular in time. We introduce DeepCare, an end-to-end deep dynamic neural network t…
We propose multivariate nonstationary Gaussian processes for jointly modeling multiple clinical variables, where the key parameters, length-scales, standard deviations and the correlations between the observed output, are all time dependent. We perform posterior inference via Hamiltonian Monte Carlo (HMC). We also prov…
Paper develops a method for valid inference using language model predictions from verbal autopsy narratives.
problem Valid inference from verbal autopsy narratives for public health decision-making.
method Develops multiPPI++ method for valid inference using NLP techniques for COD prediction.
result Demonstrates the effectiveness of multiPPI++ in handling transportability issues and recovering ground truth estimates.
Probabilistic methods improve SHM by learning from noisy, incomplete data.
problem Noisy and incomplete SHM data, lack of prior labels.
method Probabilistic algorithms for semi-supervised, active, and multi-task learning.
result Probabilistic methods enhance SHM by incorporating new data.
Bayesian model predicts mental health symptoms from IAT data, improving accuracy over D-score.
problem Limited predictive performance of D-score method for mental health assessment.
method Sparse hierarchical Bayesian model leveraging multi-modal data.
result AUCs of 0.73 (E-IAT) and 0.76 (PSY-IAT) in best modality configurations, significant after FDR correction.
New method for accurate Bayesian inference in GLMMs for large-scale data.
problem Challenges in scalable Bayesian inference for GLMMs due to intractable marginal likelihood and high computational cost.
method Stochastic gradient Markov Chain Monte Carlo (SGMCMC) algorithm using Fisher's identity for gradient estimation.
result Accurate posterior inference in large-sample settings with properly calibrated uncertainty.
Physics-informed model predicts beam stiffness and monitors structural health.
problem Predicting and monitoring the stiffness of Euler-Bernoulli beams.
method Physics-informed Gaussian process model using the Euler-Bernoulli beam equation.
result Model accurately predicts bending stiffness and detects structural damage.
Estimates causal effect of managed care plans on NYC Medicaid spending.
problem Generalizing causal estimates to a target population not well-represented by randomized studies.
method Conditional cross-design synthesis estimators combining randomized and observational data.
result Estimates causal effect of managed care plans on health care spending.
New method uses probabilistic independence to discover disease signatures from medical records.
problem Insufficiently precise diagnosis of clinical disease leading to treatment failures.
method Unsupervised machine learning using probabilistic independence to disentangle disease patterns.
result Inferred 2000 clinical disease signatures from medical records, improving cancer prediction.
TRESNET estimates exposure shifts with neural networks, improving causal inference.
problem Estimating the effect of distribution shift in treatment variables.
method Targeted Regularization for Exposure Shifts with Neural Networks (TRESNET).
result TRESNET provides robustness and efficiency guarantees for SRF estimation.
TMLE improves unbiased estimation in public health studies.
problem Improving unbiased estimation in observational studies.
method Targeted Maximum Likelihood Estimation (TMLE) integrates machine learning and statistical theory.
result TMLE has been adopted by researchers worldwide, especially outside the US.
The ubiquity of smartphone usage in many people's lives make it a rich source of information about a person's mental and cognitive state. In this work we analyze 12 weeks of phone usage data from 113 older adults, 31 with diagnosed cognitive impairment and 82 without. We develop structured models of users' smartphone i…
Bayesian predictive inference analyzes a dataset to make predictions about new observations. When a model does not match the data, predictive accuracy suffers. We develop population empirical Bayes (POP-EB), a hierarchical framework that explicitly models the empirical population distribution as part of Bayesian analys…
A new RL framework evaluates dynamic mediation effects over time.
problem Dynamic mediation effects in sequentially assigned treatments.
method Reinforcement Learning framework for decomposition and estimation of causal effects.
result Superior performance demonstrated through numerical studies and real data analysis.
AirRL uses RL to infer urban air quality from selected stations.
problem Inferring fine-grained urban air quality from limited monitoring stations.
method Reinforcement learning model with a dynamic station selector and air quality regressor.
result AirRL achieves highest performance in air quality inference experiments.
Due to the recent advancements in wearables and sensing technology, health scientists are increasingly developing mobile health (mHealth) interventions. In mHealth interventions, mobile devices are used to deliver treatment to individuals as they go about their daily lives. These treatments are generally designed to im…
VBphenoR uses variational Bayes for EHR-based patient phenotyping.
problem Phenotyping patients from EHR data for targeted treatments.
method Variational Bayes Gaussian Mixture Model (GMM) and logistic regression.
result Closed-form inference for efficient patient phenotype determination.
Prognostics and Health Management (PHM) is an emerging engineering discipline which is concerned with the analysis and prediction of equipment health and performance. One of the key challenges in PHM is to accurately predict impending failures in the equipment. In recent years, solutions for failure prediction have evo…
In the scenario of real-time monitoring of hospital patients, high-quality inference of patients' health status using all information available from clinical covariates and lab tests is essential to enable successful medical interventions and improve patient outcomes. Developing a computational framework that can learn…
Bayesian networks learn sub-population differences from data.
problem Inference from a single network structure can be misleading when data populations are heterogeneous.
method A mixture of Bayesian networks where component probabilities depend on individual characteristics.
result Identifies both network structures and demographic predictors of sub-population membership.
Study finds macroeconomic indicators predict health workforce and infrastructure measures.
problem Evaluating the predictive value of macroeconomic indicators for public health targets.
method Examined multiple forecasting approaches including neural networks, generalized additive models, random forests, and time series models with exogenous indicators.
result Macroeconomic indicators provide consistent and reproducible predictive signals for health workforce and infrastructure measures, but less so for other targets.
The paper develops a method to optimize individualized treatment rules for cost-effectiveness.
problem Developing cost-effective individualized treatment rules for healthcare policy.
method Using conditional random forest and net-monetary-benefit (NMB) to estimate optimal CE-ITR.
result The approach optimizes healthcare resource allocation by maximizing health gains and minimizing costs.
Study uses machine learning to predict future health from various health data types.
problem Predicting future health using diverse health data types.
method Applied machine learning (neural networks and XGBoost) to longitudinal data from 6830 individuals.
result Health-related measures were the strongest predictors of future health status, while genetic data performed poorly.