A locally-built, LLM-digested index of recent arXiv papers in quant finance, geometry/topology, and statistical ML — keyword search served straight from SQLite on this machine.
Bayesian meta-learning predicts Alzheimer's disease progression.
Proposes Ada-Sit method for mortality prediction of rare diseases.
For many complex diseases, there is a wide variety of ways in which an individual can manifest the disease. The challenge of personalized medicine is to develop tools that can accurately predict the trajectory of an individual's disease, which can in turn enable clinicians to optimize treatments. We represent an indivi…
Deep Belief Network predicts lncRNA-disease associations with high accuracy.
Disease-gene prediction (DGP) refers to the computational challenge of predicting associations between genes and diseases. Effective solutions to the DGP problem have the potential to accelerate the therapeutic development pipeline at early stages via efficient prioritization of candidate genes for various diseases. In…
Graph network predicts circRNA-disease associations using multi-source similarity features.
Bayesian approach models neurodegenerative diseases without clinical labels.
Study compares machine learning and process-based models for predicting rice blast disease.
Improves disease progression prediction using auxiliary surrogate labels and health markers.
MicroRNAs (miRNAs) play crucial roles in multifarious biological processes associated with human diseases. Identifying potential miRNA-disease associations contributes to understanding the molecular mechanisms of miRNA-related diseases. Most of the existing computational methods mainly focus on predicting whether a miR…
Graph Attention Networks predict disease state from single-cell data.
Prediction of the future trajectory of a disease is an important challenge for personalized medicine and population health management. However, many complex chronic diseases exhibit large degrees of heterogeneity, and furthermore there is not always a single readily available biomarker to quantify disease severity. Eve…
Bayesian hypergraph inference models disease pathways from EHR data.
Quick and accurate medical diagnosis is crucial for the successful treatment of a disease. Using machine learning algorithms, we have built two models to predict a hematologic disease, based on laboratory blood test results. In one predictive model, we used all available blood test parameters and in the other a reduced…
Disease progression models are instrumental in predicting individual-level health trajectories and understanding disease dynamics. Existing models are capable of providing either accurate predictions of patients prognoses or clinically interpretable representations of disease pathophysiology, but not both. In this pape…
New method uses probabilistic independence to discover disease signatures from medical records.
The paper predicts diseases using both clinical and genomics data.
Method predicts disease outbreaks using search logs, overcoming instability.
HMRNN combines HMMs and neural networks for Alzheimer's disease forecasting.
Alzheimer's disease (AD) is a degenerative brain disease impairing a person's ability to perform day to day activities. The clinical manifestations of Alzheimer's disease are characterized by heterogeneity in age, disease span, progression rate, impairment of memory and cognitive abilities. Due to these variabilities, …
New model predicts banana disease risk from climate data.
PHIBP predicts infectious disease outbreaks in sparse data regions.
We propose a method to predict the subject-specific longitudinal progression of brain structures extracted from baseline MRI, and evaluate its performance on Alzheimer's disease data. The disease progression is modeled as a trajectory on a group of diffeomorphisms in the context of large deformation diffeomorphic metri…
Electronic health records (EHRs) have contributed to the computerization of patient records and can thus be used not only for efficient and systematic medical services, but also for research on biomedical data science. However, there are many missing values in EHRs when provided in matrix form, which is an important is…
Geometric deep learning provides a principled and versatile manner for the integration of imaging and non-imaging modalities in the medical domain. Graph Convolutional Networks (GCNs) in particular have been explored on a wide variety of problems such as disease prediction, segmentation, and matrix completion by levera…
Most approaches to machine learning from electronic health data can only predict a single endpoint. Here, we present an alternative that uses unsupervised deep learning to simulate detailed patient trajectories. We use data comprising 18-month trajectories of 44 clinical variables from 1908 patients with Mild Cognitive…
Identifies patient-specific root causes of disease using structural equation models.
Enhances disease progression modeling using LLMs for complex brain connectivity.
Semi-supervised GAN creates synthetic genetic data for disease prediction.
VEGN uses graph neural networks to predict disease-causing mutations from genetic variants.
Multi-modal data comprising imaging (MRI, fMRI, PET, etc.) and non-imaging (clinical test, demographics, etc.) data can be collected together and used for disease prediction. Such diverse data gives complementary information about the patientś condition to make an informed diagnosis. A model capable of leveraging the i…
A novel method predicts shape development using Riemannian shape spaces.
New method predicts AD progression using MEG brain networks.
Develops a two-stage conformal prediction method for Parkinson's disease medication needs.
Early detection of preventable diseases is important for better disease management, improved inter-ventions, and more efficient health-care resource allocation. Various machine learning approacheshave been developed to utilize information in Electronic Health Record (EHR) for this task. Majorityof previous attempts, ho…
Given genetic variations and various phenotypical traits, such as Magnetic Resonance Imaging (MRI) features, we consider two important and related tasks in biomedical research: i)to select genetic and phenotypical markers for disease diagnosis and ii) to identify associations between genetic and phenotypical data. Thes…
Today, despite decades of developments in medicine and the growing interest in precision healthcare, vast majority of diagnoses happen once patients begin to show noticeable signs of illness. Early indication and detection of diseases, however, can provide patients and carers with the chance of early intervention, bett…
Deep Rule Forests identifies drug-drug and drug-disease interactions causing AKI.
Ensemble model predicts AD progression from CN status with high accuracy.
Comorbid diseases co-occur and progress via complex temporal patterns that vary among individuals. In electronic health records we can observe the different diseases a patient has, but can only infer the temporal relationship between each co-morbid condition. Learning such temporal patterns from event data is crucial f…
The widespread digitization of patient data via electronic health records (EHRs) has created an unprecedented opportunity to use machine learning algorithms to better predict disease risk at the patient level. Although predictive models have previously been constructed for a few important diseases, such as breast cance…
Omics-GAN uses GANs to generate synthetic multi-omics data for improved disease prediction.
Deep learning predicts AMD progression from longitudinal fundus images.
In this work, we consider the problem of predicting the course of a progressive disease, such as cancer or Alzheimer's. Progressive diseases often start with mild symptoms that might precede a diagnosis, and each patient follows their own trajectory. Patient trajectories exhibit wild variability, which can be associate…
Method learns drug-disease representations for repositioning opportunities.
Case vs control comparisons have been the classical approach to the study of neurological diseases. However, most patients will not fall cleanly into either group. Instead, clinicians will typically find patients that cannot be classified as having clearly progressed into the disease state. For those subjects, very lit…
CASCADE improves uncertainty communication in Parkinson's disease medication management.
Study uses machine learning and survival analysis to predict CKD progression.