A locally-built, LLM-digested index of recent arXiv papers in quant finance, geometry/topology, and statistical ML — keyword search served straight from SQLite on this machine.
Proposes a new model for predicting chronic conditions over time.
In this work we investigate intra-day patterns of activity on a population of 7,261 users of mobile health wearable devices and apps. We show that: (1) using intra-day step and sleep data recorded from passive trackers significantly improves classification performance on self-reported chronic conditions related to ment…
Enhances generative model for clinical data privacy and accuracy.
Chronicals boosts LLM fine-tuning speed by 3.51x over Unsloth.
Purpose - Functional bowel diseases, including irritable bowel syndrome, chronic constipation, and chronic diarrhea, are some of the most common diseases seen in clinical practice. Many patients describe a range of triggers for altered bowel consistency and symptoms. However, characterization of the relationship betwee…
RL algorithms with medical integration improve personalized treatment recommendations.
Simulation framework assesses ROI of chronic disease adherence and policy timing.
New fair regression method improves fairness in chronic kidney disease classification.
Sufficient physical activity and restful sleep play a major role in the prevention and cure of many chronic conditions. Being able to proactively screen and monitor such chronic conditions would be a big step forward for overall health. The rapid increase in the popularity of wearable devices provides a significant new…
Study uses machine learning and survival analysis to predict CKD progression.
Novel framework detects CKD in diabetic patients using sparse EHR representations.
Study reviews machine learning techniques for stress monitoring.
FILTER model uses fusion penalized logistic threshold regression for high-dimensional data with unknown cut points.
Machine learning predicts obesity causes using genetic and imaging data.
Prediction of the future trajectory of a disease is an important challenge for personalized medicine and population health management. However, many complex chronic diseases exhibit large degrees of heterogeneity, and furthermore there is not always a single readily available biomarker to quantify disease severity. Eve…
One primary task of population health analysis is the identification of risk factors that, for some subpopulation, have a significant association with some health condition. Examples include finding lifestyle factors associated with chronic diseases and finding genetic mutations associated with diseases in precision he…
Obstructive sleep apnea is a serious condition causing a litany of health problems especially in the pediatric population. However, this chronic condition can be treated if diagnosis is possible. The gold standard for diagnosis is an overnight sleep study, which is often unobtainable by many potentially suffering from …
Managing patients with chronic diseases is a major and growing healthcare challenge in several countries. A chronic condition, such as diabetes, is an illness that lasts a long time and does not go away, and often leads to the patient's health gradually getting worse. While recent works involve raw electronic health re…
This work proposes a new algorithm for automated and simultaneous phenotyping of multiple co-occurring medical conditions, also referred as comorbidities, using clinical notes from the electronic health records (EHRs). A basic latent factor estimation technique of non-negative matrix factorization (NMF) is augmented wi…
Deep learning predicts drug prescriptions across global health records.
Drawing an inspiration from behavioral studies of human decision making, we propose here a general parametric framework for a reinforcement learning problem, which extends the standard Q-learning approach to incorporate a two-stream framework of reward processing with biases biologically associated with several neurolo…
We study the behavior of a Time-Aware Long Short-Term Memory Autoencoder, a state-of-the-art method, in the context of learning latent representations from irregularly sampled patient data. We identify a key issue in the way such recurrent neural network models are being currently used and show that the solution of the…
Smart bin monitors predict medication adherence with high accuracy.
Study uses interviews to automatically detect BD and BPD with good accuracy.
In the presence of a layer of metaprobabilities (from uncertainty concerning the parameters), the asymptotic tail exponent corresponds to the lowest possible tail exponent regardless of its probability. The problem explains "Black Swan" effects, i.e., why measurements tend to chronically underestimate tail contribution…
Study discovers patterns in insulin needs for T1D patients.
We investigate the use of self-tracking data and unsupervised mixed-membership models to phenotype endometriosis. Endometriosis is a systemic, chronic condition of women in reproductive age and, at the same time, a highly enigmatic condition with no known biomarkers to monitor its progression and no established staging…
This paper develops explainable treatment policies for RPM using clinical knowledge.
FINs enhance performance in diverse datasets like finance, speech, and health.
Physical activity levels are an important predictor of cardiovascular health and increasingly being measured by sensors, like accelerometers. Accelerometers produce rich multivariate data that can inform important clinical decisions related to individual patients and public health. The CHAMPION study, a study of youth …
Deep learning has demonstrated success in health risk prediction especially for patients with chronic and progressing conditions. Most existing works focus on learning disease Network (StageNet) model to extract disease stage information from patient data and integrate it into risk prediction. StageNet is enabled by (1…
An optimal dynamic treatment regime (DTR) consists of a sequence of decision rules in maximizing long-term benefits, which is applicable for chronic diseases such as HIV infection or cancer. In this paper, we develop a novel angle-based approach to search the optimal DTR under a multicategory treatment framework for su…
A method models continuous-time glucose distributions in children with diabetes.
Clinical researchers use disease progression models to understand patient status and characterize progression patterns from longitudinal health records. One approach for disease progression modeling is to describe patient status using a small number of states that represent distinctive distributions over a set of obser…
Respiratory infections and chronic respiratory diseases impose a heavy health burden worldwide. Coughing is one of the most common symptoms of many such infections, and can be indicative of flare-ups of chronic respiratory diseases. Whether at a clinical or public health level, the capacity to identify bouts of coughin…
Modeling disease progression in healthcare administrative databases is complicated by the fact that patients are observed only at irregular intervals when they seek healthcare services. In a longitudinal cohort of 76,888 patients with chronic obstructive pulmonary disease (COPD), we used a continuous-time hidden Markov…
Proposes a fusion method for many treatment groups in ITRs.
In this paper, the development of a probabilistic network for the diagnosis of acute cardiopulmonary diseases is presented. This paper is a draft version of the article published after peer review in 2018 (https://doi.org/10.1002/bimj.201600206). A panel of expert physicians collaborated to specify the qualitative part…
Ankle sprains and instability are major public health concerns. Up to 70% of individuals do not fully recover from a single ankle sprain and eventually develop chronic ankle instability (CAI). The diagnosis of CAI has been mainly based on self-report rather than objective biomechanical measures. The goal of this study …
Maps of brain microarchitecture are important for understanding neurological function and behavior, including alterations caused by chronic conditions such as neurodegenerative disease. Techniques such as knife-edge scanning microscopy (KESM) provide the potential for whole organ imaging at sub-cellular resolution. How…
A new algorithm discovers causal factors between T2DM and bone mineral density.
High quality risk adjustment in health insurance markets weakens insurer incentives to engage in inefficient behavior to attract lower-cost enrollees. We propose a novel methodology based on Markov Chain Monte Carlo methods to improve risk adjustment by clustering diagnostic codes into risk groups optimal for health ex…
A typical problem in causal modeling is the instability of model structure learning, i.e., small changes in finite data can result in completely different optimal models. The present work introduces a novel causal modeling algorithm for longitudinal data, that is robust for finite samples based on recent advances in st…
A Convolutional Neural Network was used to predict kidney function in patients with chronic kidney disease from high-resolution digital pathology scans of their kidney biopsies. Kidney biopsies were taken from participants of the NEPTUNE study, a longitudinal cohort study whose goal is to set up infrastructure for obse…
LMM predicts healthcare costs and risks with improved accuracy.
Veterans with mild traumatic brain injury (mTBI) have reported auditory and visual dysfunction that persists beyond the acute incident. The etiology behind these symptoms is difficult to characterize with current clinical imaging. These functional deficits may be caused by shear injury or micro-bleeds, which can be det…
Proposes a tool to contrast global vs personalized models in clinical prediction.
Study examines biases in clinical word embeddings, revealing performance gaps across groups.