Deep learning predicts response to HER2-targeted breast cancer therapy.
arXiv research
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CAST models time-varying treatment effects in cancer patients.
Reinforcement learning algorithms are gaining popularity in fields in which optimal scheduling is important, and oncology is not an exception. The complex and uncertain dynamics of cancer limit the performance of traditional model-based scheduling strategies like Optimal Control. Motivated by the recent success of mode…
Optimal treatment regimes (OTR) are individualised treatment assignment strategies that identify a medical treatment as optimal given all background information available on the individual. We discuss Bayes optimal treatment regimes estimated using a loss function defined on the bivariate distribution of dichotomous po…
Physics-Informed Neural Networks (PINNs) benchmarked against clinical estimator and reveal parameter identifiability
In many real life problems, objects are described by large number of binary features. For instance, documents are characterized by presence or absence of certain keywords; cancer patients are characterized by presence or absence of certain mutations etc. In such cases, grouping together similar objects/profiles based o…
New methods use RL and DA to improve dosing precision and reduce side effects.
Cardiotoxicity related to cancer therapies has become a serious issue, diminishing cancer treatment outcomes and quality of life. Early detection of cancer patients at risk for cardiotoxicity before cardiotoxic treatments and providing preventive measures are potential solutions to improve cancer patients's quality of …
DSL estimates heterogeneous treatment effects over time in survival settings.
End-to-end pipeline for data-driven decision making in mixed-integer optimization.
Bayesian model for cost-effectiveness analysis with subgroup discovery.