Machine learning improves detection of Brugada Syndrome from ECGs.
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Syndrome differentiation in Traditional Chinese Medicine (TCM) is the process of understanding and reasoning body condition, which is the essential step and premise of effective treatments. However, due to its complexity and lack of standardization, it is challenging to achieve. In this study, we consider each patient'…
Syndromic surveillance detects and monitors individual and population health indicators through sources such as emergency department records. Automated classification of these records can improve outbreak detection speed and diagnosis accuracy. Current syndromic systems rely on hand-coded keyword-based methods to parse…
Data mining revealed a cluster of economic, psychological, social and cultural indicators that in combination predicted corruption and wealth of European nations. This prosperity syndrome of self-reliant citizens, efficient division of labor, a sophisticated scientific community, and respect for the law, was clearly di…
Cluster analysis aims at separating patients into phenotypically heterogenous groups and defining therapeutically homogeneous patient subclasses. It is an important approach in data-driven disease classification and subtyping. Acute coronary syndrome (ACS) is a syndrome due to sudden decrease of coronary artery blood f…
Improved logistic regression for multi-omics data improves prediction and variable selection.
Generative AI decodes quantum codes without labeled data.
In this work, we utilize Machine Learning for early recognition of patients at high risk of acute respiratory distress syndrome (ARDS), which is critical for successful prevention strategies for this devastating syndrome. The difficulty in early ARDS recognition stems from its complex and heterogenous nature. In this s…
Heart disease remains the leading cause of death in the United States. Compared with risk assessment guidelines that require manual calculation of scores, machine learning-based prediction for disease outcomes such as mortality can be utilized to save time and improve prediction accuracy. This study built and evaluated…
Predicting the risk of mortality for patients with acute myocardial infarction (AMI) using electronic health records (EHRs) data can help identify risky patients who might need more tailored care. In our previous work, we built computational models to predict one-year mortality of patients admitted to an intensive care…
The paper prices a new life insurance policy for couples, considering various contingent benefits.
We construct and analyze a family of low-density parity check (LDPC) quantum codes with a linear encoding rate, polynomial scaling distance and efficient decoding schemes. The code family is based on tessellations of closed, four-dimensional, hyperbolic manifolds, as first suggested by Guth and Lubotzky. The main contr…
Patients who suffer an acute coronary syndrome are at elevated risk for adverse cardiovascular events such as myocardial infarction and cardiovascular death. Accurate assessment of this risk is crucial to their course of care. We focus on estimating a patient's risk of cardiovascular death after an acute coronary syndr…
This paper automates mining of COVID-19 scholarly articles using machine learning.
Bayesian deep learning predicts satellite collisions.
A Convolutional Neural Network was used to predict kidney function in patients with chronic kidney disease from high-resolution digital pathology scans of their kidney biopsies. Kidney biopsies were taken from participants of the NEPTUNE study, a longitudinal cohort study whose goal is to set up infrastructure for obse…
Develops a risk score to assist ECMO planning for critically ill patients with viral or unspecified pneumonia.
Falling in Parkinsonian syndromes (PS) is associated with postural instability and consists a common cause of disability among PS patients. Current posturographic practices record the body's center-of-pressure displacement (statokinesigram) while the patient stands on a force platform. Statokinesigrams, after appropria…
Purpose - Functional bowel diseases, including irritable bowel syndrome, chronic constipation, and chronic diarrhea, are some of the most common diseases seen in clinical practice. Many patients describe a range of triggers for altered bowel consistency and symptoms. However, characterization of the relationship betwee…
Harmonization schemes limit accuracy due to domain information.
Olympic Games consistently exceed budgets, leading to unpredictable costs.
Accounting frameworks follow stipulations of existing Accounting Theories. This exploratory research sets out to trace the evolution of accounting theories of Charge and Discharge Syndrome and the Corollary of Double Entry. Furthermore, it dives into the theories of Income Determination, garnishing it with areas of div…
Mobile electrocardiogram (ECG) recording technologies represent a promising tool to fight the ongoing epidemic of cardiovascular diseases, which are responsible for more deaths globally than any other cause. While the ability to monitor one's heart activity at any time in any place is a crucial advantage of such techno…
The paper proposes a method to predict the performance of data-driven algorithms using surrogate models.
Twin-to-twin transfusion syndrome treatment requires fetoscopic laser photocoagulation of placental vascular anastomoses to regulate blood flow to both fetuses. Limited field-of-view (FoV) and low visual quality during fetoscopy make it challenging to identify all vascular connections. Mosaicking can align multiple ove…
Study improves LLMs for PPI analysis by addressing uncertainty.
Cryptofinance generates yield through innovative decentralized finance.
Deep neural network identifies potential SARS-CoV-2 inhibitors.
An optimal dynamic treatment regime (DTR) consists of a sequence of decision rules in maximizing long-term benefits, which is applicable for chronic diseases such as HIV infection or cancer. In this paper, we develop a novel angle-based approach to search the optimal DTR under a multicategory treatment framework for su…
Medical researchers are coming to appreciate that many diseases are in fact complex, heterogeneous syndromes composed of subpopulations that express different variants of a related complication. Time series data extracted from individual electronic health records (EHR) offer an exciting new way to study subtle differen…
Study repurposes open data to find potential COVID-19 drugs.
AI and HPC help screen millions of molecules for SARS-CoV-2 treatments.
Early and accurate identification of parkinsonian syndromes (PS) involving presynaptic degeneration from non-degenerative variants such as Scans Without Evidence of Dopaminergic Deficit (SWEDD) and tremor disorders, is important for effective patient management as the course, therapy and prognosis differ substantially …
Deep learning ensembles improve COVID-19 detection from chest X-rays.
DeTraC CNN detects COVID-19 from chest X-rays with high accuracy.
Many complex disease syndromes such as asthma consist of a large number of highly related, rather than independent, clinical phenotypes, raising a new technical challenge in identifying genetic variations associated simultaneously with correlated traits. In this study, we propose a new statistical framework called grap…
ECGDetect uses deep learning to detect ischemia in heart ECGs.
A typical problem in causal modeling is the instability of model structure learning, i.e., small changes in finite data can result in completely different optimal models. The present work introduces a novel causal modeling algorithm for longitudinal data, that is robust for finite samples based on recent advances in st…
A basic question in the theory of fault-tolerant quantum computation is to understand the fundamental resource costs for performing a universal logical set of gates on encoded qubits to arbitrary accuracy. Here we consider qubits encoded with constant space overhead (i.e. finite encoding rate) in the limit of arbitrari…
Causal modeling has long been an attractive topic for many researchers and in recent decades there has seen a surge in theoretical development and discovery algorithms. Generally discovery algorithms can be divided into two approaches: constraint-based and score-based. The constraint-based approach is able to detect co…
Machine learning aids in diagnosing Parkinson's disease with higher accuracy.
Study tackles variable selection with missing covariates and outcomes using machine learning and imputation.
Predictive models identify patients at risk of severe COVID-19.
Background: Elderly patients with MODS have high risk of death and poor prognosis. The performance of current scoring systems assessing the severity of MODS and its mortality remains unsatisfactory. This study aims to develop an interpretable and generalizable model for early mortality prediction in elderly patients wi…
Acute Kidney Injury (AKI) is a common clinical syndrome characterized by the rapid loss of kidney excretory function, which aggravates the clinical severity of other diseases in a large number of hospitalized patients. Accurate early prediction of AKI can enable in-time interventions and treatments. However, AKI is hig…
A new bandit problem where experiments can be interrupted if results are not promising.