Deep RL improves blood glucose control for T1D patients.
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Computational Drug Repositioning (CDR) is the task of discovering potential new indications for existing drugs by mining large-scale heterogeneous drug-related data sources. Leveraging the patient-level temporal ordering information between numeric physiological measurements and various drug prescriptions provided in E…
Blood glucose value prediction is an important task in diabetes management. While it is reported that glucose concentration is sensitive to social context such as mood, physical activity, stress, diet, alongside the influence of diabetes pathologies, we need more research on data and methodologies to incorporate and ev…
New method estimates effects of multiple nutrients on blood glucose.
A deep learning network was used to predict future blood glucose levels, as this can permit diabetes patients to take action before imminent hyperglycaemia and hypoglycaemia. A sequential model with one long-short-term memory (LSTM) layer, one bidirectional LSTM layer and several fully connected layers was used to pred…
New model predicts blood glucose in diabetics with improved accuracy.
Machine learning detects subtle glucose changes for early diabetes diagnosis.
With continuous glucose monitoring (CGM), data-driven models on blood glucose prediction have been shown to be effective in related work. However, such (CGM) systems are not always available, e.g., for a patient at home. In this work, we conduct a study on 9 patients and examine the online predictability of data-driven…
Framework generates personalized insulin treatment strategies using deep models.
In many forecasting applications, it is valuable to predict not only the value of a signal at a certain time point in the future, but also the values leading up to that point. This is especially true in clinical applications, where the future state of the patient can be less important than the patient's overall traject…
Continuous Glucose Monitoring (CGM) has enabled important opportunities for diabetes management. This study explores the use of CGM data as input for digital decision support tools. We investigate how Recurrent Neural Networks (RNNs) can be used for Short Term Blood Glucose (STBG) prediction and compare the RNNs to con…
CTRNNs improve blood glucose forecasting in ICU, outperforming traditional models.
Neural system optimizes glucose levels in diabetics.
Daytime hypoglycemia should be accurately predicted to achieve normoglycemia and to avoid disastrous situations. Hypoglycemia, an abnormally low blood glucose level, is divided into daytime hypoglycemia and nocturnal hypoglycemia. Many studies of hypoglycemia prevention deal with nocturnal hypoglycemia. In this paper, …
Paper proposes a DRL-based controller for networked AP systems that reduces communication frequency.
Modern treatments for Type 1 diabetes (T1D) use devices known as artificial pancreata (APs), which combine an insulin pump with a continuous glucose monitor (CGM) operating in a closed-loop manner to control blood glucose levels. In practice, poor performance of APs (frequent hyper- or hypoglycemic events) is common en…
\begin{abstract} We model individual T2DM patient blood glucose level (BGL) by stochastic process with discrete number of states mainly but not solely governed by medication regimen (e.g. insulin injections). BGL states change otherwise according to various physiological triggers which render a stochastic, statisticall…
Patients with Type I Diabetes (T1D) must take insulin injections to prevent the serious long term effects of hyperglycemia - high blood glucose (BG). Patients must also be careful not to inject too much insulin because this could induce hypoglycemia (low BG), which can potentially be fatal. Patients therefore follow a …
Study discovers patterns in insulin needs for T1D patients.
Hybrid model learns interpretable meal-level glycemic control.
Modeling glucose distribution changes over time using neural ODEs.
The vision for precision medicine is to use individual patient characteristics to inform a personalized treatment plan that leads to the best healthcare possible for each patient. Mobile technologies have an important role to play in this vision as they offer a means to monitor a patient's health status in real-time an…
Paper uses RL to optimize daily step distribution for better health biomarkers.
New framework predicts 5-year glucose values with missing data.
Most existing algorithms for dictionary learning assume that all entries of the (high-dimensional) input data are fully observed. However, in several practical applications (such as hyper-spectral imaging or blood glucose monitoring), only an incomplete fraction of the data entries may be available. For incomplete sett…
HAD-Net forecasts glucose levels with insights into insulin and carbs diffusion.
Neural network training entails heavy computation with obvious bottlenecks. The Compute Unified Device Architecture (CUDA) programming model allows us to accelerate computation by passing the processing workload from the CPU to the graphics processing unit (GPU). In this paper, we leveraged the power of Nvidia GPUs to …
Estimating the effect of a treatment on a given outcome, conditioned on a vector of covariates, is central in many applications. However, learning the impact of a treatment on a continuous temporal response, when the covariates suffer extensively from measurement error and even the timing of the treatments is uncertain…
A method models continuous-time glucose distributions in children with diabetes.
Paper presents estimators for entropy and information in probabilistic models.
Study improves mortality prediction in hospital patients using comprehensive feature engineering.
A framework detects nonlinear and interaction effects in epidemiological data with uncertainty quantification.
New MMD estimators detect differences in missing paired data.
Many sequential decision-making tasks require choosing at each decision step the right action out of the vast set of possibilities by extracting actionable intelligence from high-dimensional data streams. Most of the times, the high-dimensionality of actions and data makes learning of the optimal actions by traditional…
CBDL uses credal sets to improve uncertainty quantification in deep learning.
Research proposes a risk-free machine learning model for COVID screening from routine blood tests.
This study automates blood cell classification using computer vision.
Study of red blood cells using elastic surface theory.
RETAIN model improves glucose forecasting for diabetics, offering both accuracy and interpretability.
CST-YOLO improves blood cell detection with YOLOv7 and CNN-Swin Transformer.
Machine learning model diagnoses COVID-19 from routine blood tests.
Develops a tool to identify abnormal blood smear results based on CBC tests.
Mathematical model describes how red blood cells return to equilibrium.
Objective: To evaluate unsupervised clustering methods for identifying individual-level behavioral-clinical phenotypes that relate personal biomarkers and behavioral traits in type 2 diabetes (T2DM) self-monitoring data. Materials and Methods: We used hierarchical clustering (HC) to identify groups of meals with simila…
New method classifies reticulocytes from red blood cells without labels.
Detecting aggressive cancer tumors using ctDNA dynamics from few blood samples.
Previous works on segmentation of SEM (scanning electron microscope) blood cell image ignore the semantic segmentation approach of whole-slide blood cell segmentation. In the proposed work, we address the problem of whole-slide blood cell segmentation using the semantic segmentation approach. We design a novel convolut…
We use a deep learning model trained only on a patient's blood oxygenation data (measurable with an inexpensive fingertip sensor) to predict impending hypoxemia (low blood oxygen) more accurately than trained anesthesiologists with access to all the data recorded in a modern operating room. We also provide a simple way…