Enhances detection of adverse drug events using diverse healthcare record data.
problem Detecting adverse drug events from mixed data types in electronic health records.
method Aggregate diagnosis codes, drug codes, and lab measurements; use recursive feature selection.
result Significant improvement in AUC using additional features, statistically significant.
This paper uses MIL and MHCNN-RNN to predict precursors to aviation safety events.
problem Identifying events that precede aviation safety incidents.
method Multiple-instance learning (MIL) framework combined with a Multi-Head Convolutional Neural Network-Recurrent Neural Network (MHCNN-RNN) architecture.
result Multiple binary classifiers outperform in predicting high speed and high path angle events during the approach phase.
New method identifies sepsis-related patient features in EMR data.
problem Identify sepsis-related patient features in EMR data.
method Linear multivariate Hawkes process model with ReLU link function, coupled with gradient-based method.
result Identifies several interpretable GC chains that precede sepsis.
Study finds non-adherence to schizophrenia meds leads to earlier adverse events.
problem Impact of medication non-adherence on adverse outcomes in schizophrenia patients.
method Survival analysis, causal inference methods (T-learner, S-learner, nearest neighbor matching), different amounts of longitudinal information.
result Non-adherence to schizophrenia meds advances adverse events by 1 to 4 months.
This review explores methods for detecting Adverse Drug Events in EHRs.
problem Detecting Adverse Drug Events (ADEs) in EHRs using temporal data.
method Examines 5 main approaches: temporal abstraction, graph-based, learning weights, and time series data.
result Challenges remain in exploiting heterogeneous temporal data for ADE detection.
Study predicts adverse events in Afghanistan using time series data.
problem Predicting the number of negative events in Afghanistan's theater of war.
method Regression analysis on time series data, non-conventional aggregation of districts, machine learning models.
result Predictive models show reasonable performance on historical data, but other variables do not improve prediction quality.
Detecting real-time price impact in algo trading
problem Identifying the impact of traders' actions on market prices
method Measuring timing synchronicity between trader actions and adverse market events
result Detecting price impact on a per-action basis
PHASE predicts surgical complications from physiological signals.
problem Predicting adverse surgical outcomes from physiological signals.
method Self-supervised transfer learning for physiological signals.
result PHASE outperforms other approaches in predicting five surgical complications.
TPSQRs model longitudinal event data, detecting ADRs from EHRs.
problem Detecting adverse drug reactions from longitudinal event data.
method Learned by estimating a collection of interrelated PSQRs, using Poisson pseudo-likelihood for estimation.
result TPSQRs effectively and efficiently recover ADR signals from EHRs.
Method detects surgical deviations during laparoscopic rectopexy.
problem Detecting deviations from standard surgical processes during laparoscopic rectopexy.
method Multi-dimensional non-linear temporal scaling with a hidden semi-Markov model.
result Over 90% accuracy in detecting deviations.
Study shows SEC crypto classification led to significant market reactions.
problem Impact of SEC classification of crypto assets as securities.
method Event study methodology focusing on explicitly named crypto assets.
result Significant adverse market reactions, with returns plummeting 12% over one week.
Paper uses rare-event simulation to analyze personalized AP controllers for T1D patients.
problem Rare adverse events in personalized AP controllers for T1D patients.
method Generative models of patient characteristics, FDA-approved T1D simulator, rare-event simulation.
result 72,000x speedup in simulation speed and 2-10x increase in adverse condition sampling.
Survival analysis in the presence of multiple possible adverse events, i.e., competing risks, is a pervasive problem in many industries (healthcare, finance, etc.). Since only one event is typically observed, the incidence of an event of interest is often obscured by other related competing events. This nonidentifiabil…
This paper reviews radar-based nowcasting techniques for short-term weather predictions.
problem Short-term weather predictions for adverse events like heavy rain and flooding.
method Analysis of existing radar-based nowcasting techniques and machine learning approaches.
result New partnerships between environmental science and machine learning can improve nowcasting.
Deep RL optimizes lab test scheduling for better patient outcomes and cost savings.
problem Redundant lab tests lead to cost and patient discomfort.
method Deep reinforcement learning for optimal scheduling.
result Deep RL policy outperforms heuristic scheduling in both accuracy and cost.
AI traders learn to exploit meta-orders from slower traders, increasing their profits.
problem Adverse selection of medium-frequency traders by high-frequency AI agents.
method Reinforcement learning in a Hawkes LOB model, with impulse control and PPO.
result AI agents can learn to capitalize on meta-orders, increasing their profits.
Learning from electronic medical records (EMR) is challenging due to their relational nature and the uncertain dependence between a patient's past and future health status. Statistical relational learning is a natural fit for analyzing EMRs but is less adept at handling their inherent latent structure, such as connecti…
auton-survival simplifies survival analysis for healthcare data.
problem Handling censored time-to-event data in healthcare.
method Open-source package for survival regression, adjustment, counterfactual estimation, phenotyping, and treatment effects.
result Demonstrates auton-survival's ability to support complex health and epidemiological questions.
The paper proposes a method to identify subgroups with different treatment effects in time-to-event data.
problem Identifying subgroups with differential treatment effects in time-to-event data.
method A mixture model with structured sparsity regularization and novel inference procedure.
result The method effectively recovers sparse phenotypes across real-world clinical studies.
Study examines tech stocks' reactions to Facebook data leak scandal.
problem Impact of Facebook data leak scandal on U.S. tech stocks.
method Clustering method to identify related companies, CAR to measure impact.
result Overall tech sector showed no adverse impact, but Facebook's performance was negatively affected.
Study finds Jamal Khashoggi's murder negatively impacts Saudi Arabia's economy.
problem Investment deterrence due to Jamal Khashoggi's murder.
method Event-study methodology and asset pricing model.
result Khashoggi's murder had a severe adverse impact on banks, financial services, and materials sectors.
Novel algorithms improve warfarin dose prediction accuracy.
problem Challenges in estimating warfarin dose due to narrow therapeutic index and individual variability.
method Stacked generalization frameworks combining different machine learning algorithms.
result Stacked algorithms outperform the IWPC MLR algorithm, especially in subgroups.
Machine learning improves CAD management outcomes.
problem Current CAD guidelines do not account for patient-specific characteristics.
method Developed binary classifiers and regression models using patient data.
result Improved health outcomes by 24.11% compared to standard care.
Paper tackles liquidation in dark pools with adverse selection, proving uniqueness of solution.
problem Liquidation in dark pools with adverse selection for multi-asset portfolios.
method Analyzes a multidimensional stochastic control problem leading to a matrix-valued BSDE with jumps and singular terminal condition.
result Proves uniqueness of solution, novel even in simplified settings.
Novel metrics improve machine learning models for ICU patient care.
problem Predicting vital sign trajectories for early detection of adverse events.
method Developed novel performance metrics aligned with clinical contexts, validated on simulated and real datasets, and optimized neural networks using these metrics.
result Neural networks trained with these metrics excel in predicting clinically significant events.
Firms delay write-downs for adverse macroeconomic and industry outcomes but not for firm-specific issues.
problem Timeliness of write-downs for adverse macroeconomic and industry outcomes versus firm-specific issues.
method Comparative analysis of write-downs driven by macroeconomic and industry outcomes versus firm-specific outcomes.
result Firms delay write-downs for adverse macroeconomic and industry outcomes but not for firm-specific issues.
With the increased availability of large databases of electronic health records (EHRs) comes the chance of enhancing health risks screening. Most post-marketing detections of adverse drug reaction (ADR) rely on physicians' spontaneous reports, leading to under reporting. To take up this challenge, we develop a scalable…
Clusters of ACS patients identified for better therapeutic stratification.
problem Data-driven classification and subtyping of ACS patients for improved treatment.
method Outcome-driven clustering using a multi-task neural network with attention.
result Seven patient clusters with distinct characteristics and risk profiles identified.
New algorithm predicts lung cancer progression and mortality.
problem Predicting semi-competing risk outcomes in lung cancer.
method Neural Expectation-Maximization algorithm for multi-state outcomes.
result Estimates non-parametric baseline hazards and risk functions.
Study fills and adverse selection effects on trading strategy simulation.
problem Effects of fill probabilities and adverse fills on trading strategy simulation.
method Stochastic optimal control market-making problem, empirical evidence on liquid futures contracts.
result Fill probabilities and adverse fills significantly affect trading strategy performance.
Non-recurring traffic congestion is caused by temporary disruptions, such as accidents, sports games, adverse weather, etc. We use data related to real-time traffic speed, jam factors (a traffic congestion indicator), and events collected over a year from Nashville, TN to train a multi-layered deep neural network. The …
ECG signal learning predicts cardiovascular death risk.
problem Scarce positive ECG event examples and class imbalance.
method Multiple instance learning framework for raw ECG signals.
result Learned risk score outperforms existing metrics.
Lapse-supported life insurance exacerbates adverse selection risks.
problem Lapse-supported life insurance increases adverse selection costs.
method Modeling 'Term to 100' contracts and analyzing three methods of managing lapse surplus.
result Adverse selection losses can be almost unlimited under certain conditions.
BAMS uses Bayesian sampling to discover AV failures more efficiently and accurately.
problem Discovering potential failure cases in autonomous vehicles efficiently and accurately.
method Bayesian adaptive multifidelity sampling (BAMS) prioritizes exploration of low performance regions.
result BAMS discovers 10 times more issues than traditional methods with narrower rate estimates.
We present the Shortfall Deviation Risk (SDR), a risk measure that represents the expected loss that occurs with certain probability penalized by the dispersion of results that are worse than such an expectation. SDR combines Expected Shortfall (ES) and Shortfall Deviation (SD), which we also introduce, contemplating t…
Survival analysis is a fundamental tool in medical research to identify predictors of adverse events and develop systems for clinical decision support. In order to leverage large amounts of patient data, efficient optimisation routines are paramount. We propose an efficient training algorithm for the kernel survival su…
The paper explains credit decisions using Shapley decomposition for adverse actions.
problem Identifying predictors responsible for adverse credit decisions.
method Develops a simple and intuitive approach based on Shapley decomposition for models with low-order interactions.
result Shows the approach generalizes to Shapley decomposition and Baseline Shapley.
Polarimetric images enhance object detection in adverse weather conditions.
problem Object detection in road scenes is challenging in adverse weather conditions.
method Combining polarimetric imaging and deep learning.
result Polarimetry improves object detection by 20% to 50% compared to conventional RGB images.
Study shows informed traders harm market makers but price discovery benefits outweigh costs.
problem Informed traders' impact on market makers' profitability.
method Agent-based model with heterogeneous learning agents, multi-agent reinforcement learning.
result Informed market order flow is harmful when aggregate informedness is low but beneficial as it increases.
Developing an Agent-Based Model to Mitigate Adverse Selection in Uniswap v3 Liquidity Providers
problem Adverse selection in Uniswap v3 liquidity providers
method Agent-Based Model incorporating blockchain microstructure and volatility dynamics
result Dynamic fee schedules improve hedged Profit and Loss for liquidity providers
We introduce a mixture model for censored durations (C-mix), and develop maximum likelihood inference for the joint estimation of the time distributions and latent regression parameters of the model. We consider a high-dimensional setting, with datasets containing a large number of biomedical covariates. We therefore p…
Study Nash competition among dealers quoting prices to clients with unknown trading motives.
problem Adverse selection and inventory costs in dealer-client interactions.
method Analyzes one-shot Nash competition with unknown client type and inventory constraints.
result Unique symmetric Nash equilibrium exists and can be characterized by a nonlinear ODE.
This paper is split in three parts: first we use labelled trade data to exhibit how market participants accept or not transactions via limit orders as a function of liquidity imbalance; then we develop a theoretical stochastic control framework to provide details on how one can exploit his knowledge on liquidity imbala…
Recurrent neural networks (RNNs) are types of artificial neural networks (ANNs) that are well suited to forecasting and sequence classification. They have been applied extensively to forecasting univariate financial time series, however their application to high frequency trading has not been previously considered. Thi…
Study finds no significant short-term impact on liquidity supply after protocol fees were reduced.
problem Liquidity provider welfare is affected by protocol fees, but the impact on liquidity supply is unclear.
method Used a matched-overlap event-study difference-in-differences design to estimate the liquidity-supply response to take-rate cuts.
result No significant short-term impact on active liquidity or local depth; no change in LP participation or composition.
Deep learning clusters patient time-series data for better prognosis.
problem Clustering time-series data for patient phenotyping and prognosis.
method Deep predictive clustering with novel loss functions for future outcome distribution.
result Model achieves superior clustering performance and identifies meaningful patient subgroups.
Develops a deep survival model for causal inference in longitudinal studies.
problem Estimating treatment effects on time-to-event outcomes in observational studies with time-dependent covariates.
method TCS model using potential outcomes framework and ensemble of recurrent subnetworks.
result Identifies conditional average treatment effects and individual treatment effect heterogeneity over time.
Framework classifies urban congestion into recurrent and non-recurrent types.
problem Classifying urban congestion into recurrent and non-recurrent types.
method Real-time distributed classification using VANET on a heterogeneous urban road network.
result Predictive accuracy of 89.17% for the boosting technique.