Hidden Markov Models analyze mobile health data to identify APNS states.
problem Subjective self-report measures of APNS lead to errors and biases.
method Exploratory hidden Markov factor models and Stabilized Expectation-Maximization algorithm.
result Identified homogeneous APNS states and dynamic transitions.
Resting-state functional Magnetic Resonance Imaging (R-fMRI) holds the promise to reveal functional biomarkers of neuropsychiatric disorders. However, extracting such biomarkers is challenging for complex multi-faceted neuropatholo-gies, such as autism spectrum disorders. Large multi-site datasets increase sample sizes…
Understanding human fetal neurodevelopment is of great clinical importance as abnormal development is linked to adverse neuropsychiatric outcomes after birth. Recent advances in functional Magnetic Resonance Imaging (fMRI) have provided new insight into development of the human brain before birth, but these studies hav…
Firms delay write-downs for adverse macroeconomic and industry outcomes but not for firm-specific issues.
problem Timeliness of write-downs for adverse macroeconomic and industry outcomes versus firm-specific issues.
method Comparative analysis of write-downs driven by macroeconomic and industry outcomes versus firm-specific outcomes.
result Firms delay write-downs for adverse macroeconomic and industry outcomes but not for firm-specific issues.
Study fills and adverse selection effects on trading strategy simulation.
problem Effects of fill probabilities and adverse fills on trading strategy simulation.
method Stochastic optimal control market-making problem, empirical evidence on liquid futures contracts.
result Fill probabilities and adverse fills significantly affect trading strategy performance.
MAGIC uncovers disease heterogeneity across brain scales.
problem Understanding distinct subtypes of brain diseases at different spatial scales.
method Multi-scale Heterogeneity Analysis and Clustering (MAGIC) using semi-supervised clustering.
result Two main subtypes of AD identified with distinct atrophy patterns.
Study finds non-adherence to schizophrenia meds leads to earlier adverse events.
problem Impact of medication non-adherence on adverse outcomes in schizophrenia patients.
method Survival analysis, causal inference methods (T-learner, S-learner, nearest neighbor matching), different amounts of longitudinal information.
result Non-adherence to schizophrenia meds advances adverse events by 1 to 4 months.
Lapse-supported life insurance exacerbates adverse selection risks.
problem Lapse-supported life insurance increases adverse selection costs.
method Modeling 'Term to 100' contracts and analyzing three methods of managing lapse surplus.
result Adverse selection losses can be almost unlimited under certain conditions.
The paper explains credit decisions using Shapley decomposition for adverse actions.
problem Identifying predictors responsible for adverse credit decisions.
method Develops a simple and intuitive approach based on Shapley decomposition for models with low-order interactions.
result Shows the approach generalizes to Shapley decomposition and Baseline Shapley.
Study shows informed traders harm market makers but price discovery benefits outweigh costs.
problem Informed traders' impact on market makers' profitability.
method Agent-based model with heterogeneous learning agents, multi-agent reinforcement learning.
result Informed market order flow is harmful when aggregate informedness is low but beneficial as it increases.
Developing an Agent-Based Model to Mitigate Adverse Selection in Uniswap v3 Liquidity Providers
problem Adverse selection in Uniswap v3 liquidity providers
method Agent-Based Model incorporating blockchain microstructure and volatility dynamics
result Dynamic fee schedules improve hedged Profit and Loss for liquidity providers
Study Nash competition among dealers quoting prices to clients with unknown trading motives.
problem Adverse selection and inventory costs in dealer-client interactions.
method Analyzes one-shot Nash competition with unknown client type and inventory constraints.
result Unique symmetric Nash equilibrium exists and can be characterized by a nonlinear ODE.
This paper is split in three parts: first we use labelled trade data to exhibit how market participants accept or not transactions via limit orders as a function of liquidity imbalance; then we develop a theoretical stochastic control framework to provide details on how one can exploit his knowledge on liquidity imbala…
We study the problem of detecting adverse drug events in electronic healthcare records. The challenge in this work is to aggregate heterogeneous data types involving diagnosis codes, drug codes, as well as lab measurements. An earlier framework proposed for the same problem demonstrated promising predictive performance…
Detecting real-time price impact in algo trading
problem Identifying the impact of traders' actions on market prices
method Measuring timing synchronicity between trader actions and adverse market events
result Detecting price impact on a per-action basis
AI traders learn to exploit meta-orders from slower traders, increasing their profits.
problem Adverse selection of medium-frequency traders by high-frequency AI agents.
method Reinforcement learning in a Hawkes LOB model, with impulse control and PPO.
result AI agents can learn to capitalize on meta-orders, increasing their profits.
MLHO predicts COVID-19 adverse outcomes using past medical records.
problem Predicting adverse outcomes after COVID-19 infection.
method Iterative feature and algorithm selection, sequential representation mining.
result Mean AUC ROC of 0.91 for mortality prediction.
Deep learning methods are increasingly being used with neuroimaging data like structural and function magnetic resonance imaging (MRI) to predict the diagnosis of neuropsychiatric and neurological disorders. For psychiatric disorders in particular, it is believed that one of the most promising modality is the resting-s…
Study compares deep learning stock trading strategies in adverse market conditions.
problem Comparing deep learning models for stock trading performance in extreme market downturns.
method Reconstructed three deep learning models and compared their strategies through trading simulations.
result Deep learning models, especially LSTM, can mitigate losses in severe market downturns.
Sunshine trading theory predicts lower execution costs and liquidity provision through explicit preannouncements, but evidence is scarce in traditional markets.
problem Adverse selection on liquidity provision
method Reconstructing metaorders and comparing them with visible TWAP executions
result Visible TWAPs face lower execution costs and leave a smaller permanent price impact compared to hidden metaorders.
New method identifies sepsis-related patient features in EMR data.
problem Identify sepsis-related patient features in EMR data.
method Linear multivariate Hawkes process model with ReLU link function, coupled with gradient-based method.
result Identifies several interpretable GC chains that precede sepsis.
PHASE predicts surgical complications from physiological signals.
problem Predicting adverse surgical outcomes from physiological signals.
method Self-supervised transfer learning for physiological signals.
result PHASE outperforms other approaches in predicting five surgical complications.
In a continuous-time setting where a risk-averse agent controls the drift of an output process driven by a Brownian motion, optimal contracts are linear in the terminal output; this result is well-known in a setting with moral hazard and -under stronger assumptions - adverse selection. We show that this result continue…
Drawing an inspiration from behavioral studies of human decision making, we propose here a more general and flexible parametric framework for reinforcement learning that extends standard Q-learning to a two-stream model for processing positive and negative rewards, and allows to incorporate a wide range of reward-proce…
A new framework detects adverse dataset shifts using outlier scores.
problem False alarms in dataset shift tests.
method Outlier scores to compare contamination rates at varying thresholds.
result Reduces the sensitivity to minor differences in predictive performance.
We prove optimal mechanisms for general contract spaces.
problem Optimal mechanism design under adverse selection and ambiguity.
method Existence proof for optimal mechanisms in general contract spaces.
result Centralized contracting is equivalent to delegated contracting.
This paper solves optimal market making for multiple goods, including bundling, under adverse selection.
problem Designing optimal market making mechanisms for multiple goods and adverse selection.
method Formulated as an optimal transport problem with geometric constraints, using differentiable economics.
result Optimal market making mechanisms can exploit bundling to improve prices and accept payments in kind.
Object detection in road scenes is necessary to develop both autonomous vehicles and driving assistance systems. Even if deep neural networks for recognition task have shown great performances using conventional images, they fail to detect objects in road scenes in complex acquisition situations. In contrast, polarizat…
This paper uses MIL and MHCNN-RNN to predict precursors to aviation safety events.
problem Identifying events that precede aviation safety incidents.
method Multiple-instance learning (MIL) framework combined with a Multi-Head Convolutional Neural Network-Recurrent Neural Network (MHCNN-RNN) architecture.
result Multiple binary classifiers outperform in predicting high speed and high path angle events during the approach phase.
Model evaluates insurance risk using thermodynamic principles.
problem Risk of lapses due to adverse selection in insurance.
method Collective model with diffusion process influenced by statistical mechanics.
result Derives level premium to evaluate insurance risk.
Proposes a framework to adjust quotes for informational risk in markets with informed traders and price-revealing quotes.
problem Informational risk in markets with informed traders and price-revealing quotes.
method Proposes a tractable framework to adjust quotes considering adverse selection and price reading.
result Market makers can adjust their quotes to better manage informational risk.
This article aims to explore an empirical approach to analyze the macroeconomicsdeterminants of default of borrowers. For this purpose, we have measured the impact of the adverse economic conditions on the degradation of the credit portfolio quality.In our paper, we have shed more light on the question of the aggravati…
India is ranked as the third most attractive nation for retail investment among emerging markets and many MNCs have been looking for the potential benefits to be taken from it. The development of organized retail has the potential of generating employment, improvement in technology, development of real estate etc. On t…
This paper improves bond market making by adjusting hit-ratios for client flow quality.
problem Economic misleading of raw hit-ratios in corporate bond market making.
method Stochastic-control framework with residual-quality-adjusted hit-ratio.
result Optimal quotes decompose into various components, improving service/economics frontier.
Cryptocurrency patterns stable across market caps, validated by microstructure theory.
problem Stable patterns in cryptocurrency microstructure across different market caps.
method Unified CatBoost modeling pipeline with time-series cross validation, validated by backtests.
result Feature rankings and partial effects are stable across assets despite heterogeneous liquidity and volatility.
A simple strategy optimizes broker-client trading, reducing price discounts for informed traders.
problem Optimizing broker-client trading to balance client flow and informed trader losses.
method Modelled as a stochastic control problem, derived optimal strategy in closed form, introduced algorithm.
result Optimal strategy reduces price discounts for informed traders, balancing client flow and informed trader losses.
New formula identifies and quantifies costs for automated market makers.
problem Adverse selection costs faced by liquidity providers in automated market makers.
method Derives a Black-Scholes-like formula for AMMs and identifies loss-versus-rebalancing cost.
result Closed-form expressions for LVR applicable to all automated market makers.
Study predicts adverse events in Afghanistan using time series data.
problem Predicting the number of negative events in Afghanistan's theater of war.
method Regression analysis on time series data, non-conventional aggregation of districts, machine learning models.
result Predictive models show reasonable performance on historical data, but other variables do not improve prediction quality.
We propose a limit order book (LOB) model with dynamics that account for both the impact of the most recent order and the shape of the LOB. We present an empirical analysis showing that the type of the last order significantly alters the submission rate of immediate future orders, even after accounting for the state of…
Study shows SEC crypto classification led to significant market reactions.
problem Impact of SEC classification of crypto assets as securities.
method Event study methodology focusing on explicitly named crypto assets.
result Significant adverse market reactions, with returns plummeting 12% over one week.
Learning from electronic medical records (EMR) is challenging due to their relational nature and the uncertain dependence between a patient's past and future health status. Statistical relational learning is a natural fit for analyzing EMRs but is less adept at handling their inherent latent structure, such as connecti…
Development of interpretable machine learning models for clinical healthcare applications has the potential of changing the way we understand, treat, and ultimately cure, diseases and disorders in many areas of medicine. These models can serve not only as sources of predictions and estimates, but also as discovery tool…
Objective: A median of 14.4% of patient undergone at least one adverse event during surgery and a third of them are preventable. The occurrence of adverse events forces surgeons to implement corrective strategies and, thus, deviate from the standard surgical process. Therefore, it is clear that the automatic identifica…
Background: The problem of predicting whether a drug combination of arbitrary orders is likely to induce adverse drug reactions is considered in this manuscript. Methods: Novel kernels over drug combinations of arbitrary orders are developed within support vector machines for the prediction. Graph matching methods are …
Sparse rewards with different magnitudes speed up learning in model-based reinforcement learning.
problem Speeding up learning in model-based reinforcement learning methods.
method Add uniformly sampled reward values to sparse binary rewards during training.
result Training can be more efficient and faster with less variability.
Transfer learning aims to improve learning in target domain by borrowing knowledge from a related but different source domain. To reduce the distribution shift between source and target domains, recent methods have focused on exploring invariant representations that have similar distributions across domains. However, w…
FLAIR measures LP competitiveness in AMMs, improving LP performance evaluations.
problem LP returns are affected by both market risk and competitive strategies.
method Introduces FLAIR metric to quantify LP competitiveness and assesses its impact on LP returns.
result FLAIR captures dynamic behavior of LPs and differentiates between active provisioning strategies.
This paper models AMM positions using CI options to calculate LVR and provide actionable guidance.
problem Calculating and managing adverse-selection costs in automated market makers (AMMs).
method Modeling AMM positions as perpetual American CI options to replicate delta and calculate LVR.
result LVR is identical to theta of CI options, and AMM positions have approximately constant LVR over long windows.